PMID: 6989755Jan 1, 1980Paper

Plasma norepinephrine variations with dietary sodium intake

Hypertension
M G NichollsJ Greenhouse

Abstract

Plasma catecholamine and renin activity levels were measured across a range of dietary sodium intakes (10--300 mEq/day) in 20 normal male volunteers. Supine plasma norepinephrine levels presented a triphasic pattern in relation to urine sodium, whereas epinephrine levels were not significantly altered by sodium intake, and renin showed the well-known hyperbolic relationship to urine sodium excretion. Highest supine norepinephrine values occurred at low salt intakes, the lowest when sodium excretion was between 100 and 180 mEq/day, and intermediate when sodium excretion was greater than 180 mEq/day. These findings show that sodium intake is an important consideration in the interpretation of plasma norepinephrine levels.

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Apr 1, 1993·Pflügers Archiv : European journal of physiology·O A SofolaB J Adegunloye
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