PMID: 2108233Apr 1, 1990Paper

Plasma retinol-binding protein response to vitamin A administration in infants susceptible to bronchopulmonary dysplasia

The Journal of Pediatrics
J P ShenaiF Chytil

Abstract

We hypothesized that changes in plasma retinol-binding protein (RBP) concentration in response to vitamin A administration might be useful for evaluating vitamin A status of very low birth weight infants susceptible to bronchopulmonary dysplasia. We prospectively studied 24 consecutively admitted neonates (birth weight less than 1350 gm, gestational age less than 31 weeks, ventilator dependent for greater than 24 hours after birth), who were eligible to receive 2000 IU supplemental vitamin A by intramuscular injection on postnatal day 1 and on alternate days thereafter for 28 days. In addition to serial assessment of vitamin A status, we measured plasma RBP just before and 1, 3, and 6 hours after an intramuscular injection of vitamin A (2000 IU/kg retinyl palmitate) on days 1 and 28. The percent increase in plasma RBP (delta-RBP) was high (mean +/- SD: 61 +/- 37%) and plasma vitamin A and RBP values were low on day 1, indicative of vitamin A deficiency. Supplemental vitamin A improved vitamin A status of all infants as shown by low delta-RBP (mean +/- SD: 8 +/- 9%) and normal plasma vitamin A and RBP values on day 28. Bronchopulmonary dysplasia was diagnosed in 12 of 24 infants. Infants with bronchopulmonary dysplasia had a hig...Continue Reading

References

Nov 1, 1979·The Journal of Pediatrics·E BancalariJ Gannon
Nov 1, 1979·The Journal of Pediatrics·D K Edwards
Jan 1, 1978·The Journal of Pediatrics·R B BrandtF E Ehrlich
Jan 1, 1978·World Review of Nutrition and Dietetics·J A Olson
May 1, 1975·Metabolism: Clinical and Experimental·Y IngenbleekM De Visscher
Aug 1, 1987·The American Journal of Clinical Nutrition·O Amedee-ManesmeJ Therasse
Dec 1, 1987·The American Journal of Clinical Nutrition·C W WoodruffJ E Hewett
Feb 1, 1985·Pediatric Research·J P ShenaiM T Stahlman
Sep 1, 1985·Pediatric Research·J P ShenaiM T Stahlman
Nov 1, 1971·The Journal of Clinical Investigation·F R Smith, D S Goodman
Feb 1, 1971·Biochemical Medicine·J N ThompsonT K Murray
Feb 16, 1967·The New England Journal of Medicine·W H NorthwayD Y Porter
Sep 1, 1968·The Journal of Clinical Investigation·M KanaiD S Goodman
Oct 1, 1984·The Journal of Pediatrics·V A HusteadR D Zachman
Jun 1, 1984·The American Journal of Clinical Nutrition·O Amédée-ManesmeJ A Olson
Jul 1, 1983·Early Human Development·J Bhatia, E E Ziegler
Oct 1, 1980·Annals of Internal Medicine·L HowardB Wolf
Oct 1, 1981·The Journal of Pediatrics·J P ShenaiF Chytil
Feb 27, 1981·Annals of the New York Academy of Sciences·L RaskP A Peterson
Aug 1, 1981·The Journal of Pediatrics·J P ShenaiM T Stahlman
Oct 1, 1981·The American Journal of Clinical Nutrition·S MobarhanH Al-Midani

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Citations

Nov 29, 2007·European Journal of Nutrition·Manuela StrobelHans-Konrad Biesalski
Oct 31, 2003·Molecular Aspects of Medicine·H K Biesalski, D Nohr
May 1, 1995·Antimicrobial Agents and Chemotherapy·K M NeuzilB S Graham
Feb 23, 2005·Archives of Disease in Childhood. Fetal and Neonatal Edition·H Mactier, L T Weaver
Dec 23, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·S P WardleN J Shaw
Feb 1, 2013·Critical Care Research and Practice·Olga Carvalho, Carlos Gonçalves
Oct 16, 2014·European Journal of Clinical Nutrition·A C LongardtA Loui
Aug 30, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·B W KramerA H Jobe
Mar 13, 2015·Frontiers in Pharmacology·Anjali Iyengar, Jonathan M Davis
Jul 30, 2002·Neonatal Network : NN·F R Greer
Mar 1, 1996·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·M K Darby, J L Loughead
May 1, 1993·JPEN. Journal of Parenteral and Enteral Nutrition·S T Robbins, A B Fletcher
Sep 22, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Andrew P FeranchakRonald J Sokol
Mar 1, 2007·Animal : an International Journal of Animal Bioscience·D Nohr, H K Biesalski
Aug 24, 2016·The Cochrane Database of Systematic Reviews·Brian A DarlowMaria Ximena Rojas-Reyes
Nov 2, 2020·Advances in Nutrition·Jesse Sheftel, Sherry A Tanumihardjo

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