Plasma SCF/c-kit Levels in Patients with Dipper and Non-Dipper Hypertension

Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih
Hai-Lan ZhongXiu-Mei Chen

Abstract

Objective The aim of this study was to investigate the relationship between peripheral plasma stem cell factor (SCF)/c-kit levels and the types of dipper and non-dipper hypertension in hypertensive patients. Methods This cross-sectional study included newly diagnosed hypertensive patients who underwent 24-hour ambulatory blood pressure monitor (ABPM) between January 2009 and 2012 in Jiangning city. Patients were divided into the dipper group and the non-dipper group according to ABPM measurements. The levels of SCF and its receptor c-kit, tumor necrosis factor-α (TNF-α) and interleukin 6 (IL-6) in peripheral blood were measured via enzyme-linked immunosorbent assays. The serum levels of glucose and lipid were examined as well. The levels of SCF/c-kit were compared between the dippers and the non-dippers; and their correlation with 24-hour mean systolic blood pressure (MSBP), 24-hour mean diastolic blood pressure (MDBP), TNF-α and IL-6 were investigated using linear regression analyses statistically. Results A total of 247 patients with newly diagnosed hypertension were recruited into the study, including 116 non-dippers and 131 dippers. The levels of peripheral plasma SCF were higher in non-dipper group (907.1±52.7 ng/L vs. 778...Continue Reading

References

Jan 6, 2007·Arteriosclerosis, Thrombosis, and Vascular Biology·Chao-Hung WangWen-Jin Cherng
Oct 9, 2007·Lancet·José BoggiaUNKNOWN International Database on Ambulatory blood pressure monitoring in relation to Cardiovascular Outcomes (IDACO) investigators
Dec 8, 2007·Stroke; a Journal of Cerebral Circulation·Hon-Kan YipHsueh-Wen Chang
Apr 23, 2008·Hypertension·Dong YouJean-Sébastien Silvestre
May 22, 2008·The Journal of Clinical Endocrinology and Metabolism·Marie-France HivertJames B Meigs
Nov 15, 2008·Molecular Medicine·Katja RabeUli C Broedl
Mar 7, 2013·Journal of Magnetic Resonance Imaging : JMRI·Gang LiuYu-Lin Wang
Apr 11, 2013·International Journal of Hypertension·Yolanda MendizábalEduardo Nava
Feb 14, 2016·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Tomasz P MikolajczykTomasz J Guzik

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