Mar 1, 1976

Plasma secretin and gastrin responses to a meat meal and duodenal acidification in dogs

The American Journal of Physiology
K Y LeeW Y Chey

Abstract

In five conscious dogs with gastric fistula and two duodenal cannulas, plasma RIA secretin and gastrin levels were determined in response to 1) infusion of 0.1 N HCl in the proximal duodenal cannula, 2) ingestion of a meal, and 3) intraduodenal infusion of 0.1 N HCl following ingestion of a meal. Significant increases in plasma RIA secretin levels occurred during duodenal acidification. However, no significant change occurred in the secretin levels after ingestion of a meal, whereas significant increase in plasma gastrin level was observed. Postprandial duodenal pH remained above 4.5 for 3 h.

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Mentioned in this Paper

Gastric Fistula
Body Parts - Cannula
Specimen Type - Cannula
Secretin Measurement
Duodenum
Acidification - ActCode
Secrepan
Fasting
Gastrin Measurement
GAST gene

About this Paper

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