PMID: 6538618Jan 1, 1984Paper

Plasma testosterone transport in primates

Journal of Steroid Biochemistry
M PugeatB C Nisula

Abstract

All primate species, including Old and New World primates and prosimians have a plasma testosterone-estradiol binding globulin (TeBG), which is a glycoprotein and has a similar mobility in polyacrylamide gel electrophoresis. In New World primates the TeBG binding capacity for [3H]testosterone was higher and its affinity lower than in Old World primates. These changes were associated with high unbound plasma testosterone concentrations in these species. Binding parameters of TeBG in prosimian species varied markedly. Thus, in primate evolution TeBG was conserved despite marked differences in binding characteristics. In New World primates changes are associated with high total and unbound testosterone, a finding concordant with alterations of other steroid hormones concentration in these species with "generalized steroid hormone resistance".

References

Dec 1, 1973·Endocrinology·F Gauthier-WrightP Mauvais-Jarvis
Jul 1, 1984·Endocrinology·M M PugeatM B Lipsett
Aug 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J M RenoirE E Baulieu
Jan 1, 1981·Endocrine Reviews·W M Pardridge
Aug 1, 1982·The Journal of Clinical Endocrinology and Metabolism·G P ChrousosM B Lipsett
Dec 28, 1964·Annals of the New York Academy of Sciences·B J DAVIS

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Citations

Jan 1, 1995·Neuroscience and Biobehavioral Reviews·D A Damassa, J M Cates
Jun 1, 2001·The Journal of Steroid Biochemistry and Molecular Biology·M I NewB O'Malley
Feb 23, 2013·Reproduction : the Official Journal of the Society for the Study of Fertility·Joachim WistubaStefan Schlatt
Aug 4, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Ramesh K ChandoliaManuela Simoni
Sep 30, 2005·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Ling-Hong LiMari S Golub

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