PMID: 9537301Apr 16, 1998Paper

Plasma total-homocysteine in anorexia nervosa

European Journal of Clinical Nutrition
D MoyanoN Lambruschini

Abstract

The measurement of plasma total-homocysteine (tHcy) as a marker of folate and cobalamin status in patients with anorexia nervosa. Plasma tHcy, folate, cobalamin and other determinants of tHcy of a random group of patients with anorexia nervosa were compared with our own reference values. The study was performed at the tertiary children's Hospital Sant Joan de Déu. All the female adolescents (n=43) coming to the Hospital during a one-year period, who were diagnosed with anorexia nervosa. Reference values for tHcy were simultaneously performed with apparently healthy adolescents (by history and analytical data) who underwent presurgical analysis for minor interventions, and other magnitudes we used our own reference values. Plasma tHcy was measured by reverse phase HPLC with fluorescence detection of the SBDF derivatives. Folate and cobalamin concentrations were determined by radioimmunoassay. tHcy was significantly increased in anorexic patients compared to reference values (Mann-Whitney, P < 0.0001-0.001). Values were above reference range in 34% of patients, and high-normal range in 53% of patients. tHcy concentrations lowered in 8 and 11 patients after nutritional rehabilitation. Cobalamin and folate were in the reference ran...Continue Reading

Citations

Dec 12, 2001·European Journal of Clinical Investigation·M A VilasecaC Fortuny
Dec 12, 2001·European Journal of Clinical Investigation·P M Ueland, A L Bjørke Monsen
Dec 1, 2004·Nutrition Research Reviews·Yves Ingenbleek, Vernon R Young
Jun 30, 2007·Cephalalgia : an International Journal of Headache·L M Cupini, E Stipa
Dec 6, 2003·Clinical Chemistry and Laboratory Medicine : CCLM·Per Magne Ueland, Anne Lise Bjørke Monsen
Mar 2, 2010·Journal of Neural Transmission·Julia WilhelmHelge Frieling
Jul 3, 2013·Nutrition Reviews·Yves Ingenbleek, Hideo Kimura
Dec 22, 2006·Journal of Psychiatric Research·Helge FrielingStefan Bleich
Apr 24, 2010·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Jessica Setnick
Mar 3, 2004·The International Journal of Eating Disorders·Josefina CastroJosep Toro
Jan 31, 2007·The International Journal of Eating Disorders·Joseph LevineDaniel Stein
Jan 30, 2004·European Journal of Clinical Nutrition·F ZengerB H Lauterburg
Jun 21, 2003·The American Journal of Clinical Nutrition·Anne Lise Bjørke Monsen, Per Magne Ueland

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