PMID: 698146Sep 1, 1978Paper

Plasma unconjugated oestriol in late pregnancy: circadian variation and the effect of meals and a glucose load

British Journal of Obstetrics and Gynaecology
M G HullM D Gillmer

Abstract

Plasma unconjugated oestriol (E3) concentrations were determined by radioimmunoassay in 10 normal subjects in late pregnancy, throughout a normal day and night, and after a 50 g oral glucose load. There was a circadian pattern in E3 concentration characterized by an abrupt increase of 15 per cent at night. There was no significant rhythm during the day or night, taken separately. However there was a 10 to 11 per cent reduction in E3 concentrations soon after some meals and after a glucose load, possibly due to expansion of the plasma volume. Excluding the effect of meals, the fluctuation of E3 concentrations in individuals (median of the coefficients of variation) was 11.5 per cent in the day. Overall, it was 13.2 per cent in the day, 12.1 per cent at night and 15.9 per cent over the whole period studied. Since the variation in plasma unconjugated E3 concentrations through 24 hours was no greater than random fluctuations or day-to-day variation there is no need to restrict the time of blood sampling in clinical practice.

References

Mar 1, 1977·British Journal of Obstetrics and Gynaecology·M D GillmerT Chard
Nov 1, 1976·British Journal of Obstetrics and Gynaecology·P C ChewS S Ratnam
Jan 1, 1967·The Journal of Clinical Endocrinology and Metabolism·R C Franks
Nov 1, 1974·The Journal of Clinical Endocrinology and Metabolism·R Goebel, E Kuss
Jan 1, 1974·Acta Obstetricia Et Gynecologica Scandinavica. Supplement·B S LindbergB A Nilsson
Apr 1, 1972·Journal of Steroid Biochemistry·M CastanierR Scholler
Oct 1, 1971·American Journal of Obstetrics and Gynecology·D TulchinskyS G Korenman
Aug 1, 1972·The Journal of Endocrinology·G M Masson, G R Wilson
Apr 1, 1971·The Journal of Obstetrics and Gynaecology of the British Commonwealth·D MacourtF Naftolin
Sep 1, 1968·The Journal of Obstetrics and Gynaecology of the British Commonwealth·A M ThomsonF E Hytten
Nov 1, 1968·The Journal of Clinical Endocrinology and Metabolism·H M BalikianJ F Tait
Feb 1, 1965·The Journal of Clinical Endocrinology and Metabolism·J F TAITJ BOUGAS

❮ Previous
Next ❯

Citations

Sep 8, 1979·British Medical Journal·B J TrudingerM E Arrans
Dec 8, 2007·Clinics in Perinatology·John D Yeast, George Lu
Aug 30, 2005·Obstetrics and Gynecology Clinics of North America·John D Yeast, George Lu
Jan 13, 2004·Clinics in Perinatology·Patrick S Ramsey, William W Andrews
Jul 4, 2015·Journal de gynécologie, obstétrique et biologie de la reproduction·C CompanD Gallot
Nov 1, 1980·British Journal of Obstetrics and Gynaecology·J R ChallisB Richardson
Jan 1, 1984·European Archives of Psychiatry and Neurological Sciences·J SchöpfP K Le
Jan 1, 1986·Critical Reviews in Clinical Laboratory Sciences·R F Vining, R A McGinley
Jan 1, 1984·Annals of Clinical Biochemistry·P E CusickW C Alston

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.