PMID: 9550460Apr 29, 1998Paper

Plasma vitamins E and C concentrations of adult patients during cardiopulmonary bypass

Journal of the American College of Nutrition
C C TangneyW Piccione

Abstract

This study was designed with two aims: 1) to determine if the coronary artery bypass graft (CABG) procedure alters plasma vitamin E and C concentrations of adult patients through repeated determinations of vitamin levels at time points before, during and following CABG, and 2) to assess whether plasma vitamin E concentrations reflect myocardial tissue content. A consecutive sample of 38 patients undergoing CABG surgery at a Midwest tertiary care hospital was enrolled. Patients receiving blood transfusions before or during surgery were excluded. Plasma vitamin E/total lipid ratios rose with reperfusion, remained elevated immediately following bypass, and fell to preoperative concentrations by 24 hours. Plasma vitamin E/total cholesterol levels varied little throughout this time course. Both plasma uric acid and ascorbate concentrations (corrected for hemodilution) also rose by the preischemic interval, and remained elevated until a return to preoperative levels by 24 hours. Corrected malondialdehyde (MDA) concentrations rose by pre-ischemia but returned more quickly to preoperative levels. Atrial appendage tissue vitamin E concentrations bore a significant relationship to those of plasma prior to surgery (r=+0.49, p=0.004). Repo...Continue Reading

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Citations

Jul 14, 2012·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·M G W van den HeuvelR R W J van der Hulst
Mar 21, 2009·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Marieke G W van den HeuvelRené R W J van der Hulst
Mar 9, 2005·Annals of the New York Academy of Sciences·A T UlusS Basu
Jun 24, 2008·Annales de cardiologie et d'angéiologie·J C MartyC Girard
Jun 25, 2017·Interactive Cardiovascular and Thoracic Surgery·Jun GengZhenya Shen

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