Plasmacytoid urothelial carcinoma of the bladder. A case report and the first description of urinary cytology

Acta Cytologica
Xin-min ZhangMyron R Melamed

Abstract

Plasmacytoid carcinomas are rare variants, and there are only a few reported examples of plasmacytoid carcinoma of the urinary bladder in the English-language literature. We now report another such case and the first in which there was examination of urinary cytology. A 79-year-old, Caucasian woman who presented with gross hematuria following a revascularization procedure on the right arm was found to have an extensive, diffuse carcinoma of the bladder. On biopsy, there were single, round and polygonal tumor cells with a striking plasmacytoid appearance infiltrating diffusely throughout the edematous lamina propria. Immunocytochemical stains confirmed an epithelial classification, and carcinoma in situ was demonstrated in the contiguous urothelium. Voided urine cytology before and after cystoscopy and biopsy demonstrated large, dyshesive tumor cells with plasmacytoid features. A case of plasmacytoid variant of urothelial carcinoma of the bladder is reported, with the first description of its urinary cytology.

Citations

Jun 6, 2009·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Mahul B Amin
Sep 8, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Matthew G LimAdeboye O Osunkoya
Apr 2, 2008·The American Journal of Surgical Pathology·Jae Y RoAlberto G Ayala
Nov 18, 2008·The American Journal of Surgical Pathology·Priya NigwekarMahul B Amin
Aug 12, 2009·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Atsunari KawashimaSusumu Miyoshi
Sep 7, 2012·Case Reports in Urology·Philippe NabboutGennady Slobodov
Jul 5, 2005·Urology·Iraklis C MitsogiannisMichael D Melekos
Jan 13, 2006·Histopathology·J D Coyne, E Sim
Nov 28, 2008·BJU International·Fabio Tavora, Jonathan I Epstein
Feb 18, 2011·Urologia Internationalis·Prodromos PhilippouDemetrios Delakas
May 3, 2012·Diagnostic Cytopathology·Koraljka Rajković MolekAntica Duletić-Načinović
Jul 12, 2008·Diagnostic Cytopathology·Guoping Cai, Anil V Parwani
Nov 8, 2007·BJU International·Antonio Lopez-BeltranRodolfo Montironi
May 22, 2009·Cytopathology : Official Journal of the British Society for Clinical Cytology·T SakumaK Kawano
Jun 1, 2006·International Journal of Urology : Official Journal of the Japanese Urological Association·Takurou KohnoToshitugu Oka
Oct 28, 2019·Diagnostic Cytopathology·Patrizia StracciaFrancesco Pierconti
Apr 27, 2021·Cancer Cytopathology·Meredith M NicholsMaria Luisa C Policarpio-Nicolas
Aug 9, 2007·Archives of Pathology & Laboratory Medicine·Qihui J ZhaiJae Y Ro
Dec 1, 2008·Surgical Pathology Clinics·Cristina Magi-GalluzziMing Zhou
May 5, 2010·Pathology·Antonio Lopez-BeltranRodolfo Montironi

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