Plasmacytoma as a Mimicker of Colonic Carcinoma in an Elderly Man

Case Reports in Pathology
Sara Mathew GeorgeSayed Ali Isa Almahari

Abstract

Multiple myeloma is a neoplastic proliferation of monoclonal plasma cells. Although it is usually restricted to the bone marrow, extraskeletal spread in the form of localised extramedullary collections of malignant plasma cells (plasmacytomas) can occur. However, gastrointestinal tract involvement in multiple myeloma is rare and overt gastrointestinal bleeding from plasmacytoma is uncommon. We report a case of colonic plasmacytoma which presented with bleeding per rectum and was initially misdiagnosed as colonic neuroendocrine carcinoma. Later the patient presented with recurrence of the colonic mass along with multiple lytic bone lesions. The diagnosis of colonic plasmacytoma with progression into multiple myeloma was given. We also discuss here the diagnostic difficulty of plasma cell neoplasms in small biopsies of the colon.

References

Feb 20, 2004·The New England Journal of Medicine·Rebecca WeintraubLee Levitt
May 2, 2007·World Journal of Surgical Oncology·Vishal GuptaPramod K Mishra
Nov 5, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anne HerbstRobert S Krouse
Sep 13, 2014·South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie·Todor RosicGladness Dakalo Nethathe
Jan 1, 2014·Ulusal cerrahi dergisi·İsmail ZihniAdam Uslu
May 12, 2015·Case Reports in Hematology·Diana TriantafyllopoulouMargaret Rokicka
Jul 24, 2015·ACG Case Reports Journal·Gaurav SyalFarshad Aduli
Aug 1, 2013·Gastroenterology Research·Seung-Hyun LeeHee-Kyung Chang

❮ Previous
Next ❯

Citations

Sep 15, 2020·International Medical Case Reports Journal·Abid M SadiqElifuraha W Mkwizu

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsies
biopsy
electrophoresis

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Case Reports in Radiology
Alexis SmithElizabeth Frauenhoffer
Clinical Case Reports
Hussein Merza, Raj Sarkar
Journal of Bronchology & Interventional Pulmonology
Erin Raci-Wetherbee, H Erhan Dincer
© 2022 Meta ULC. All rights reserved