PMID: 6536669Jan 1, 1984Paper

Plasmapheresis versus lymphoplasmapheresis in rheumatoid arthritis: immunologic comparisons and literature review

Journal of Clinical Apheresis
D J WallaceD Goldfinger

Abstract

Eight patients with Functional Class III, seropositive, erosive rheumatoid arthritis unresponsive to remittive drugs each underwent nine aphereses over 3 weeks. Four had a 40-ml/kg plasma exchange and four others had a 40-ml/kg plasma exchange plus a mean 5.67 X 10(9) lymphocyte depletion. Both groups appeared to improve clinically. T and B cell counts and OK T4 and OK T8 ratios decreased in the lymphoplasmapheresis group. Phytohemagglutinin stimulation decreased in lymphoplasmapheresis and increased in plasmapheresis patients with significant comparisons (p = 0.02). These findings confirm and extend previous work. Plasmapheresis and lymphoplasmapheresis appear to have fundamentally different actions on lymphocyte function.

References

Oct 1, 1979·Arthritis and Rheumatism·J A GoldmanS B Miller
Oct 1, 1978·Annals of the Rheumatic Diseases·J S PercyE Brisson
Jul 1, 1977·Arthritis and Rheumatism·H E PaulusN S MacDonald
Feb 1, 1979·Annals of the Rheumatic Diseases·J TenenbaumJ E Curtis
Jul 1, 1979·Arthritis and Rheumatism·D J WallaceJ R Klinenberg
May 12, 1983·The New England Journal of Medicine·I L DwoshT P Anastassiades
Oct 22, 1981·The New England Journal of Medicine·B L KotzinH S Kaplan
Jul 1, 1981·Arthritis and Rheumatism·J KarshM W Flye
Jun 10, 1982·The New England Journal of Medicine·D WallaceJ R Klinenberg
Jul 1, 1980·The American Journal of Medicine·M Kosaka, A Solomon
Jul 1, 1980·Arthritis and Rheumatism·R S RothwellJ S Percy

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Citations

May 4, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·H Ogawa, Y Matsumoto
May 4, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·K Sawada, T Shimoyama
Jan 1, 1993·Journal of Clinical Apheresis·D D KiprovB C McLeod
Jan 1, 1988·Journal of Clinical Apheresis·P S MalcheskyY Nosé
Feb 1, 1997·Rheumatic Diseases Clinics of North America·R Ramsey-Goldman, E Schilling
May 26, 1999·Lupus·D J Wallace

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