PMID: 1061089Dec 1, 1975

Plasmid interactions in Staphylococcus aureus: nonadditivity of compatible plasmid DNA pools

Proceedings of the National Academy of Sciences of the United States of America
C Ruby, R P Novick

Abstract

Six different Staphylococcus aureus plasmids have been examined for compatibility relationships and their intracellular DNA pools have been measured singly and in various combinations. All six were mutually compatible, but contrary to expectation, their intracellular DNA pools were not additive; instead, there appeared to be a maximum level of extrachromosomal DNA that could be supported by the cell, and the plasmids studied approached this level individually as well as in varous combinations. One exception was encountered: a plasmid encoding kanamycin/neomycin resistance was present in a small but constant number of copies regardless of the presence of other plasmids.

References

Jun 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·K TimmisS N Cohen
Apr 5, 1975·Journal of Molecular Biology·R J Sheehy, R P Novick
Dec 1, 1973·Journal of General Microbiology·I ChopraR W Lacey
Apr 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·D B Clewell, D R Helinski
May 1, 1967·Proceedings of the National Academy of Sciences of the United States of America·R RadloffJ Vinograd

Citations

Aug 1, 1986·Molecular & General Genetics : MGG·S J Projan, R P Novick
Dec 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·A Goze, S D Ehrlich
Mar 29, 2000·Journal of Bacteriology·Neville FirthR A Skurray
Sep 1, 1987·Plasmid·I UchidaN Terakado
Sep 1, 1978·Plasmid·R P Novick, F C Hoppensteadt
Nov 1, 1980·Plasmid·S Iordănescu, M Surdeanu
Dec 9, 2017·Frontiers in Microbiology·Stephen M KwongNeville Firth

Related Concepts

DNA, Bacterial
DNA, Circular
Antibiotic Resistance, Microbial
Cytoplasmic Inheritance
Kantrex
Episomes
Staphylococcus aureus
Transduction, Genetic

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