PMID: 2494049Mar 1, 1989Paper

Plasminogen activator and its inhibitor in the experimental corneal wound

Experimental Eye Research
T TervoA Tarkkanen

Abstract

Anterior keratectomy was performed to 10 eyes of 8 adult rabbits. The animals were killed 3-24 hr after wound closure. The corneas were excised and subjected to histochemical demonstration of urokinase-type plasminogen activator (u-PA), tissue-type PA (t-PA) and plasminogen activator inhibitor [PAI-1) using commercial antibodies. A strong immunoreaction for u-PA, a weaker reaction for PAI-1 and a very weak t-PA-like immunoreaction appeared in the anterior stroma of the wounded area. None of the antisera used showed any immunostaining in the cornea outside the wound. The role of the plasminogen activator-plasmin system in the healing of the corneal wound is discussed.

References

Feb 1, 1987·Acta Ophthalmologica·E M SalonenA Vaheri
Jan 1, 1985·Advances in Cancer Research·K DanøL Skriver
Jan 1, 1986·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·E Lantz, M Pandolfi
Jul 1, 1985·Klinische Monatsblätter für Augenheilkunde·J P Harnisch, P K Sinha
Jun 25, 1984·FEBS Letters·E M SalonenA Vaheri
Jul 1, 1983·Archives of Ophthalmology·T NishidaR Manabe

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Citations

Jan 1, 1994·Documenta Ophthalmologica. Advances in Ophthalmology·N B ChesnokovaN E Sosulina
Jul 1, 1995·Molecular and Biochemical Parasitology·M M MitraJ Y Niederkorn
Sep 5, 2002·Progress in Retinal and Eye Research·Haydee Bazan, Paulo Ottino
May 24, 2008·Journal of Cataract and Refractive Surgery·Adrienne CsutakAndrás Berta
Jan 18, 2005·Experimental Eye Research·Zhiyu WangMichelle Kurpakus-Wheater
Feb 1, 1990·Experimental Eye Research·G B van SettenA Vaheri
Dec 16, 2005·Current Eye Research·Aidee AyalaBeatrice Y J T Yue
Aug 1, 1997·Current Eye Research·M SakataA R Beaton
Aug 1, 1990·Acta Ophthalmologica·L JoutsimoT Tervo
Jan 1, 1992·Acta Ophthalmologica. Supplement·T TervoA Tarkkanen
Aug 1, 1991·Acta Ophthalmologica·J Tözsér, A Berta

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