PMID: 6409270Jul 23, 1983Paper

Plasmodial pigmentation of placenta and outcome of pregnancy in West African mothers

British Medical Journal
M Watkinson, D I Rushton

Abstract

In a region where falciparum malaria is endemic and where pregnant women traditionally receive only curative treatment for parasitaemias and no chemoprophylaxis 65 placental biopsy specimens were examined histologically for malaria pigment. Twenty seven placentas had pigment, but parasitaemias had been diagnosed antenatally in only 12 of these women despite their frequent attendance at antenatal and other clinics. The incidence of parasitaemia in pregnant primigravidas was 17.7%, seven times greater than that in lactating primiparous mothers; pregnant primigravidas also had the highest incidence (67%) of pigmented placentas. First born babies with pigmented placentas had a mean (SD) birth weight of 2580 (260) g, significantly less than the 3150 (400) g of unaffected first babies. All babies weighing less than 2500 g at birth had pigmented placentas. Pigmentation was associated with parasitaemias in the second half of pregnancy, and, although some recovery from early parasitaemias may occur, the fetoplacental unit is inadequately protected by curative treatment alone. Chemoprophylaxis currently remains the procedure of choice.

References

Aug 17, 1974·British Medical Journal·J D Macgregor, J G Avery
Apr 1, 1973·Archives of Disease in Childhood·M J BruetonR Prosser
Jul 1, 1970·The Journal of Pediatrics·L M DubowitzC Goldberg
Sep 1, 1968·The Journal of Obstetrics and Gynaecology of the British Commonwealth·A M ThomsonF E Hytten
Jan 1, 1980·Transactions of the Royal Society of Tropical Medicine and Hygiene·R M GalbraithR S Bray
Dec 1, 1981·Annals of Tropical Paediatrics·M B RaghuK Gupta
Jan 1, 1980·Transactions of the Royal Society of Tropical Medicine and Hygiene·R M GalbraithW P Faulk
Sep 1, 1952·Annals of Tropical Medicine and Parasitology·L J BRUCE-CHWATT
Oct 11, 1958·British Medical Journal·D S CANNON
Dec 20, 1958·British Medical Journal·H M ARCHIBALD
Mar 14, 1964·British Medical Journal·D MORLEYW F CUTHBERTSON

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Citations

Jan 1, 1996·Immunologic Research·M P Piccinni, S Romagnani
Jan 1, 1985·Transactions of the Royal Society of Tropical Medicine and Hygiene·M WatkinsonP G Lunn
Jul 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·A F Fleming
Sep 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·B M GreenwoodA B Hatib-N'Jie
Sep 1, 1992·Transactions of the Royal Society of Tropical Medicine and Hygiene·A M GreenwoodB M Greenwood
Sep 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·C MenendezB M Greenwood
Oct 1, 1986·Parasitology Today·R E Phillips, D A Warrell
Apr 1, 1996·Parasitology Today·A D Sullivan, S R Meshnick
Apr 15, 2004·Placenta·B J BrabinJ Ordi
Jan 31, 2002·Transactions of the Royal Society of Tropical Medicine and Hygiene·H L Guyatt, R W Snow
Sep 10, 2002·The Journal of Emergency Medicine·David A JerrardAmal Mattu
Jun 12, 2003·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Dietlind SchleiermacherOdile Mercereau-Puijalon
Feb 19, 2008·The Journal of Infectious Diseases·Philippe BoeufStephen J Rogerson
Oct 12, 2010·The Journal of Infectious Diseases·Atis MuehlenbachsPatrick E Duffy
Apr 2, 2010·International Journal of Epidemiology·Thomas P EiseleRichard W Steketee
May 1, 1995·American Journal of Reproductive Immunology : AJRI·F SabahiL D Frenkel
Apr 17, 2012·Malaria Journal·Machteld E BoelRose McGready
Nov 2, 2005·PLoS Medicine·Theonest K MutabingwaPatrick E Duffy
Nov 3, 2010·The American Journal of Tropical Medicine and Hygiene·Falgunee K ParekhOralee H Branch
Jul 8, 2011·The American Journal of Tropical Medicine and Hygiene·Nana O WilsonJonathan K Stiles
May 1, 2012·Journal of Neuroparasitology·Sarah Hochman, Kami Kim
Sep 2, 1999·Lancet·F NostenN J White
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A SowunmiA O Arowojolu
May 1, 1991·Annals of Human Biology·R A Primhak, D F MacGregor
Aug 25, 2004·Trends in Parasitology·François NostenBernard Brabin
Mar 1, 1992·The Journal of Infection·T T WarnerE G Wilkins
Mar 4, 2015·Parasitology·A R D McLeanF J I Fowkes
Apr 19, 2015·Malaria Journal·Faith I OnditiHastings S Ozwara
Jun 2, 2000·Placenta·A D SullivanS R Meshnick
Nov 18, 2005·Reproductive Toxicology·Robert L Brent
Mar 1, 1993·Histopathology·J N BulmerB M Greenwood
Apr 3, 2013·The American Journal of Tropical Medicine and Hygiene·Jaime Carmona-FonsecaAmanda Maestre
Nov 4, 2000·Nature Medicine·B PouvelleJ Gysin
Feb 1, 1990·Annals of Tropical Medicine and Parasitology·B J BrabinJ Paino
Jan 1, 1989·Transactions of the Royal Society of Tropical Medicine and Hygiene·S Goriup

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