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Plasmodium falciparum in owl monkeys: drug resistance and chloroquine binding capacity

Science

Jul 17, 1970

C D Fitch

Abstract

Erythrocytes infected with chloroquine-sensitive Plasmodium falciparum bind chloroquine with an apparent intrinsic association constant of 1.5 x 10(7) liters per mole. Such high-affinity binding of chloroquine is absent or deficient in uninfected erythrocytes and in erythrocytes infecte...read more

Mentioned in this Paper

Antibiotic Resistance, Microbial
Receptors, Drug
Malaria
Monkey Diseases
Anthropoidea
Erythrocytes
Plasmodium falciparum
Carbon Isotopes
Metazoa
Nivaquine
17
Paper Details
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Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Chloroquine resistance in malaria: a deficiency of chloroquine binding

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 1, 1969
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Plasmodium falciparum in owl monkeys: drug resistance and chloroquine binding capacity

Science

Jul 17, 1970

C D Fitch

PMID: 4988896

DOI: 10.1126/science.169.3942.289

Abstract

Erythrocytes infected with chloroquine-sensitive Plasmodium falciparum bind chloroquine with an apparent intrinsic association constant of 1.5 x 10(7) liters per mole. Such high-affinity binding of chloroquine is absent or deficient in uninfected erythrocytes and in erythrocytes infecte...read more

Mentioned in this Paper

Antibiotic Resistance, Microbial
Receptors, Drug
Malaria
Monkey Diseases
Anthropoidea
Erythrocytes
Plasmodium falciparum
Carbon Isotopes
Metazoa
Nivaquine
17

Similar Papers Found In These Feeds

Plasmodium Falciparum

Malaria remains a major cause of morbidity and mortality in the tropics, with the parasite Plasmodium falciparum responsible for the majority of the disease burden. Discover the latest research on Plasmodium falciparum.

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Chloroquine resistance in malaria: a deficiency of chloroquine binding

Proceedings of the National Academy of Sciences of the United States of AmericaDecember 1, 1969
C D Fitch
Paper Details
References
  • References
  • Citations96
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations96
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