PMID: 6411067May 15, 1983Paper

Platelet-activating factor stimulates phosphatidylinositol turnover in human platelets

The Biochemical Journal
D E MacIntyre, W K Pollock


Platelet-activating factor stimulates phosphatidylinositol turnover in human platelets as indicated by [32P]phosphatidate accumulation in platelets pre-labelled with [32P]Pi, and by [3H]phosphatidate accumulation and [3H]phosphatidylinositol loss in platelets pre-labelled with [3H]arachidonate. These effects of platelet-activating factor are direct and are independent of the production and/or release of endogenous platelet agonists such as ADP, 5-hydroxytryptamine and thromboxane A2.


Jan 1, 1986·Annals of the New York Academy of Sciences·T J ResinkF R Bühler
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