PMID: 9549612Apr 29, 1998Paper

Platelet adhesion onto chargeable functional group gradient surfaces

Journal of Biomedical Materials Research
J H LeeH B Lee

Abstract

Functional group gradients were prepared on low-density polyethylene (PE) sheets. The surface density of grafted functional groups was gradually changed along the sample length by way of corona discharge treatment with gradually increasing power following graft copolymerization of acrylic acid (AA), sodium p-styrene sulfonate (NaSS), or N,N-dimethyl aminopropyl acrylamide (DMAPAA). AA and NaSS are negatively chargeable and DMAPAA is positively chargeable in phosphate-buffered saline or plasma solution at pH 7.3-7.4. The prepared functional group gradient surfaces were characterized by measurement of the water contact angle, by electron spectroscopy for chemical analysis, and by Fourier transform infrared spectroscopy in the attenuated total reflectance mode. All these measurements indicated that the functional groups were grafted onto the PE surfaces with gradually increasing density. The platelets adhered to the functional group gradient surfaces along the sample length were counted and observed by scanning electron microscopy. It was observed that the platelet adhesion to the gradient surfaces decreased gradually with the increasing surface density of functional groups. This may be related to the hydrophilicity of the surface...Continue Reading

References

Oct 1, 1992·Journal of Biomedical Materials Research·K LewandowskaL A Culp
Apr 1, 1990·Journal of Biomedical Materials Research·K SmetanaJ Sulc
Dec 1, 1993·Journal of Biomedical Materials Research·T Okada, Y Ikada
Jan 1, 1993·Journal of Biomaterials Science. Polymer Edition·J H Lee, H B Lee
Mar 1, 1996·Journal of Biomedical Materials Research·E Kulik, Y Ikada

❮ Previous
Next ❯

Citations

Jan 15, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Ashwin NairLiping Tang
Sep 23, 2008·Tissue Engineering. Part B, Reviews·Milind SinghMichael S Detamore
Jul 27, 2001·Journal of Biomaterials Science. Polymer Edition·C W Lin, J C Lin
Nov 26, 1999·Journal of Biomedical Materials Research·C D McFarlandK E Healy
Apr 24, 2008·Journal of Biomedical Materials Research. Part a·Ling-Shu Wan, Zhi-Kang Xu
Jul 16, 2010·Journal of Biomedical Materials Research. Part a·Joshua A HorwitzCynthia A Reinhart-King
Jun 7, 2013·Interface Focus·Jindan WuChangyou Gao
Feb 3, 2018·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Naveen KumarShankar Sharma
Oct 6, 2001·Journal of Biomaterials Science. Polymer Edition·L BacákováV Hnatowicz
Jun 23, 2010·Journal of Biomaterials Science. Polymer Edition·Junichiro SarukawaHiroshi Tamura
May 29, 2016·Biointerphases·Brooke L FarrugiaMegan S Lord
May 21, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Chunming LiJinghua Yin
Oct 14, 2004·Journal of Biomedical Materials Research. Part a·George K ToworfePaul Ducheyne
May 23, 2014·Journal of Materials Science. Materials in Medicine·Finosh Gnanaprakasam Thankam, Jayabalan Muthu
Jun 12, 2003·Journal of Biomaterials Applications·Manfred F MaitzIgor Tsyganov
Apr 14, 2020·Materials Science & Engineering. C, Materials for Biological Applications·Quanchao ZhangHonglin Luo
Aug 27, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Tobias EkbladBo Liedberg
May 11, 2021·Advanced Composites and Hybrid Materials·Ting HeZhaoliang Cui
Jun 24, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Yong-Xue DingVladimir Hlady
Jul 23, 2014·ACS Applied Materials & Interfaces·Chunming LiJinghua Yin
Aug 9, 2007·Colloids and Surfaces. B, Biointerfaces·Zuwei MaChangyou Gao
Dec 31, 2010·Biomacromolecules·Francesca IntranuovoRoberto Gristina
Feb 13, 2010·Biomaterials·Lindsey E Corum, Vladimir Hlady

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.