PMID: 9549627Apr 29, 1998Paper

Platelet adhesion onto segmented polyurethane surfaces modified by PEO- and sulfonated PEO-containing block copolymer additives

Journal of Biomedical Materials Research
J H LeeY H Kim

Abstract

Polyethylene oxide (PEO) surfaces were prepared by the addition of PEO- and sulfonated PEO-containing amphiphilic block copolymers as surface-modifying additives in a segmented polyurethane (PU). PEO-PPO-PEO triblock copolymers (Pluronics) with different PEO chain lengths (from 2 to 80) were used as additives. The prepared film surfaces were characterized by the measurement of dynamic water contact angles and electron spectroscopy for chemical analysis. It was observed that the PU films containing 10 wt% of PEO additives were surface-saturated with the additives regardless of their PEO chain length, but the PEO chains were more projected from the film surfaces containing the additives with longer PEO chains. The water absorption of the films increased largely with the increasing PEO chain length of the additives. The addition of PEO additives produced film surfaces that were in a gel-like state. The films demonstrated some extraction of the PEO additives. However, the additives with higher molecular weights were entrapped more stably into the PU matrix. The mechanical properties (tensile strength and elongation) of the films were changed by the addition of PEO additives, but the differences were not significant compared to the ...Continue Reading

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Citations

Jul 9, 1999·Journal of Biomedical Materials Research·J H LeeY M Ju
Mar 12, 2003·Biomaterials·M C L MartinsM A Barbosa
Aug 1, 2000·Colloids and Surfaces. B, Biointerfaces·H J LeeY H Kim
Dec 18, 2002·Journal of Biomaterials Science. Polymer Edition·Y L YuanS C Lin
Aug 17, 2002·Journal of Biomaterials Science. Polymer Edition·Jae Hyung Park, You Han Bae
Apr 27, 2005·Journal of Biomaterials Science. Polymer Edition·L PoussardC Bunel
Oct 21, 2009·Nanomedicine·Xue LiMarek W Radomski
Dec 15, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Hironori YamazoeToshizumi Tanabe
Nov 1, 2015·Colloids and Surfaces. B, Biointerfaces·Era JainAshok Kumar
Aug 2, 2008·Journal of Biomedical Materials Research. Part a·Qiaoyan LiuGuo-Qiang Chen
May 15, 2013·Journal of Biomedical Materials Research. Part a·Changlai ZhuTianyi Zhang
Apr 7, 2012·International Journal of Biomaterials·Brahatheeswaran DhandayuthapaniD Sakthikumar
May 29, 2016·Biointerphases·Brooke L FarrugiaMegan S Lord
Sep 12, 2000·Journal of Biomaterials Science. Polymer Edition·M Morra
Dec 3, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Keith R MilnerAlan J Snyder
Nov 10, 2005·Journal of Biomedical Materials Research. Part a·Keith R MilnerChristopher A Siedlecki
Sep 30, 2008·Pharmaceutical Development and Technology·Yuan-Ching TaiD Q Wang
Mar 29, 2000·Journal of Biomedical Materials Research·P BanerjeeL G Griffith
Nov 7, 2017·Polymer Chemistry·Melissa L HawkinsMelissa A Grunlan
Oct 1, 2012·Materials Science & Engineering. C, Materials for Biological Applications·N GomathiS Neogi

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