May 1, 1981

Platelet adhesiveness, plasma fibrinogen, and fibrinolytic activity in juvenile-onset and maturity-onset diabetes mellitus

Journal of Clinical Pathology
S C Sharma


The nature of vascular disease and its complications are different in juvenile-onset (JOD) and maturity-onset (MOD) diabetes mellitus. In order to explore the disturbances in the coagulation-fibrinolytic system, platelet adhesiveness, plasma fibrinogen, and euglobulin lysis time were estimated in 26 cases of MOD. Two groups of age- and sex-matched controls were also studied. Platelet adhesiveness and plasma fibrinogen were essentially normal while euglobulin lysis time was significantly decreased in the JOD group. The MOD group, on the other hand, showed a reversed pattern in the form of enhanced platelet adhesiveness and plasma fibrinogen and no compensatory increase in fibrinolysis.

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Mentioned in this Paper

Diabetes Mellitus, Non-Insulin-Dependent
Platelet Adhesiveness
Assay of Fibrinolysis
Vascular Diseases
Euglobulin Lysis Time Measurement
Diabetes, Autoimmune
Blood Coagulation
Diabetes Mellitus

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