PMID: 6107502Oct 18, 1980Paper

Platelet aggregates in peripheral and coronary-sinus blood in patients with spontaneous coronary-artery spasm

Lancet
R M RobertsonJ Hawiger

Abstract

Five out of twenty patients with vasotonic angina had frequent spontaneous attacks with dramatic ST-segment alterations. These attacks were consistently associated with an increase in platelet aggregates in coronary-sinus blood but not arterial blood. This increase in platelet aggregates during coronary-artery spasm suggests a potential causal role for the platelet in this subset of patients with ischaemic heart-disease. However, the increase in platelet aggregates could be secondary to reduced coronary blood-flow.

Citations

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