PMID: 9532848May 1, 1997Paper

Platelet aggregation and lipoprotein levels in a patient with familial hypercholesterolemia after selective LDL-apheresis

São Paulo Medical Journal = Revista Paulista De Medicina
M N ParesS P Bydlowski

Abstract

Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after apheresis selective for low-density lipoprotein (LDL), a lipid-lowering procedure. This treatment reduced plasmatic levels of total and LDL-cholesterol, apo B, and triglyceride. Increased platelet aggregation was reduced immediately after the apheresis in whole blood as well as in platelet-rich plasma. However, aggregation in washed platelets remained unchanged after LDL-apheresis. In conclusion, in this patient reduction of LDL-cholesterol improved platelet function in the very short term.

References

Jul 1, 1994·European Journal of Clinical Investigation·A BröijersénP Hjemdahl
Apr 1, 1993·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·I VirgoliniH Sinzinger

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Citations

Apr 30, 2013·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Jae Hoon ChungTae Hyo Kim

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