Platelet count and early outcome in patients with spontaneous cerebellar hemorrhage: a retrospective study

PloS One
Ching-Yueh LinYung-Tsan Wu

Abstract

The importance of coagulation, hematology, and biochemical variables have been investigated in the stroke population but have not been systemically surveyed in cerebellar hemorrhage (CH) population. The aim of the study was to explore the predictive value of these factors for early outcome in this population. Eighty patients with acute spontaneous CH were retrospectively analyzed. Clinical and laboratory data were collected on admission for analysis. The patients were divided by Glasgow outcome scale (GOS) score at discharge into the good outcome group (GOS score 4 or 5) and the poor outcome group (GOS score 1, 2, or 3). The association between early outcome and clinical or laboratory variables were investigated by binary logistic regression. There were 46 (57.5%) patients in the poor outcome group and 34 (42.5%) in the good outcome group. The platelet count (PC) was significantly lower in the poor outcome group (187.3 ± 53.0 × 10(9)/l) compared with good outcome group (244.9 ± 63.9 × 10(9)/l) (p < 0.001). Moreover, PC (OR 0.97; p = 0.004) was the strong predictor with poor early outcome. We firstly show that lower PC is the independent predictor for poor early outcome in patients with spontaneous CH.

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Citations

Jun 12, 2019·Journal of Clinical Medicine·Tsung-Han LeeAij-Lie Kwan
Oct 28, 2019·Platelets·Farzaneh SadeghiAmir Houshang Shemirani
Mar 9, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Chuanyuan TaoChao You
Jun 10, 2021·International Journal of Clinical Practice·Yu-Ping ShenYung-Tsan Wu
Oct 14, 2021·Seminars in Thrombosis and Hemostasis·Hau C Kwaan

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