PMID: 1563330Feb 1, 1992Paper

Platelet function in male diabetics with and without macrovascular complications

Diabetes Research and Clinical Practice
L TóthL Romics


Changes of platelet aggregation in relation to macroangiopathy and to some of its risk factors were observed in microangiopathy-free, well-controlled type 1 diabetic males. Platelet aggregate ratio was generally lower in patients (n = 77) than in age-matched healthy subjects (n = 48). In the absence of cigarette smoking, hypertension, obesity and hypercholesterolemia (n = 25) in vitro platelet hyperaggregation was found induced with epinephrine, collagen or arachidonic acid, and to a lesser degree with ADP. There was no change in the presence of at least one risk factor in addition to diabetes (n = 29), but there was a further significant increase in platelet aggregation when overt coronary, cerebral or peripheral artery disease was present (n = 23).


Jan 1, 1978·Diabetes·T KuzuyaH Kajinuma
Mar 1, 1975·The Journal of Clinical Investigation·S J ShattilR A Cooper
Feb 21, 1991·The American Journal of Medicine·L Raij
Oct 1, 1986·Journal of Hypertension·D ValtierP Meyer
Feb 20, 1986·The New England Journal of Medicine·R Ross
Apr 24, 1987·JAMA : the Journal of the American Medical Association·K M AndersonD Levy
Feb 9, 1985·British Medical Journal·T W MeadeG J Miller
Sep 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·F MelaniD F Steiner
Nov 30, 1983·The American Journal of Medicine·J A ColwellP V Halushka
Jan 1, 1982·Acta Haematologica·J W DavisP E Phillips
Jun 1, 1982·Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie·G E HoffmannS Hoffmann
Apr 15, 1982·Thrombosis Research·M Aviram, G J Brook
Feb 1, 1981·Archives of Internal Medicine·J W Davis, R F Davis

❮ Previous
Next ❯


Dec 17, 1997·Clinical Biochemistry·L Mazzanti, B Mutus
Sep 25, 1999·Thrombosis Research·M PütterP Rohdewald
May 16, 2000·Diabetes Research and Clinical Practice·L TóthL Kammerer
Jul 7, 2000·Integrative Medicine : Integrating Conventional and Alternative Medicine·M Araghi-NiknamR R Watson
Nov 5, 2019·Acta Diabetologica·Christian KringPernille J Vinholt

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.