PMID: 1563330Feb 1, 1992Paper

Platelet function in male diabetics with and without macrovascular complications

Diabetes Research and Clinical Practice
L TóthL Romics

Abstract

Changes of platelet aggregation in relation to macroangiopathy and to some of its risk factors were observed in microangiopathy-free, well-controlled type 1 diabetic males. Platelet aggregate ratio was generally lower in patients (n = 77) than in age-matched healthy subjects (n = 48). In the absence of cigarette smoking, hypertension, obesity and hypercholesterolemia (n = 25) in vitro platelet hyperaggregation was found induced with epinephrine, collagen or arachidonic acid, and to a lesser degree with ADP. There was no change in the presence of at least one risk factor in addition to diabetes (n = 29), but there was a further significant increase in platelet aggregation when overt coronary, cerebral or peripheral artery disease was present (n = 23).

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Citations

Dec 17, 1997·Clinical Biochemistry·L Mazzanti, B Mutus
Sep 25, 1999·Thrombosis Research·M PütterP Rohdewald
May 16, 2000·Diabetes Research and Clinical Practice·L TóthL Kammerer
Jul 7, 2000·Integrative Medicine : Integrating Conventional and Alternative Medicine·M Araghi-NiknamR R Watson
Nov 5, 2019·Acta Diabetologica·Christian KringPernille J Vinholt

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