Platelet heterogeneity and dense tubular system changes on activation

Experientia
R YaromY Havivi

Abstract

Platelets impregnated with heavy metals appeared as 3 distinct morphological types: 'reticular' cells with a polygonal dense tubular network and stained granules, dark metallophilic cells, and pale metallophobic cells with microvesicles and non-staining granules. On stimulation, type 1 cells decreased while type 3 cells increased, suggesting that with activation dense tubules break up into microvesicles and granules become metallophobic. In the type 2 cells a different functional mechanism may exist.

References

Dec 1, 1976·British Journal of Haematology·D G PeningtonA E Roxburgh
Feb 1, 1975·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·T SatoT C Detwiler
Jan 1, 1972·Annual Review of Medicine·S Karpatkin
Apr 1, 1980·European Journal of Clinical Investigation·R YaromG C Robin

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Citations

Jan 1, 1982·The Histochemical Journal·R YaromS Meyer
Jan 1, 1987·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·S MeyerR Yarom

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