PMID: 11604565Oct 18, 2001Paper

Platelet kinetics in immune thrombocytopenic purpura and human immunodeficiency virus thrombocytopenia

Current Opinion in Hematology
C A Leissinger

Abstract

Platelet kinetics studies are capable of measuring in vivo platelet survival and platelet turnover rates. These studies can be helpful in elucidating mechanisms of thrombocytopenia, particularly in complicated clinical situations. Numerous studies over the past 30 years have established the abnormalities in platelet kinetics associated with immune thrombocytopenic purpura (ITP). It is now well known that many patients infected with HIV type-1 will develop thrombocytopenia, and that at least 10% will develop a thrombocytopenic disorder clinically indistinguishable from immune thrombocytopenic purpura. Platelet kinetics studies in this group of patients may prove of great benefit in understanding the mechanisms underlying thrombocytopenia and in making accurate diagnoses. For all patients with ITP-like disorders, these studies may also prove helpful in understanding and improving current therapies.

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Citations

Feb 1, 1996·Seminars in Oncology Nursing·K M Shuey
Feb 8, 2016·American Journal of Hematology·Doris QuonJennifer Maahs
Nov 19, 2003·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Zaidoon OwaisChristopher G Cumming
Mar 23, 2005·The Journal of Infection·Mathias LichterfeldJuergen K Rockstroh
Aug 17, 2012·Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur̈ Transfusionsmedizin Und Immunham̈atologie·Oliver MeyerAbdulgabar Salama
Jun 24, 2008·Ultrastructural Pathology·Etheresia PretoriusCarl R Franz

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