PMID: 36192Apr 1, 1979

Platelet monoamine oxidase activity in schizophrenia. Relationship to disease, treatment, institutionalization and outcome

The British Journal of Psychiatry : the Journal of Mental Science
J Mann, K M Thomas


A study was made of platelet monoamine oxidase (MAO) activity in non-medicated, newly-admitted schizophrenics and institutionalized chronic schizophrenics both on and off medication. These patients were compared to two control groups: normal subjects and brain-damaged institutionalized patients. No relationship was found between platelet MAO activity and the severity or duration of illness, duration of psychotropic medication, presence of auditory hallucinations or institutionalization. Mean platelet MAO activity did not differ significantly between the schizophrenic subgroups and control groups. Thirty-one patients studied before and after treatment with phenothiazines showed no significant change in platelet MAO activity. The findings did not indicate a relationship between schizophrenia, its treatment or outcome and platelet MAO activity.


Jan 1, 1975·Folia Psychiatrica Et Neurologica Japonica·S TakahashiN Tani
Jul 17, 1976·Lancet·J R Smythies
Sep 1, 1978·Journal of Neurology, Neurosurgery, and Psychiatry·J Mann, E Chiu
Dec 28, 1977·Archiv für Psychiatrie und Nervenkrankheiten·L DemischN Seiler
Jan 1, 1976·Schizophrenia Bulletin·R J Wyatt, D L Murphy
Oct 1, 1977·The American Journal of Psychiatry·J SullivanC Dackis
Jul 1, 1974·Biochemical Genetics·C R Wrathall, E L Tatum
Jan 1, 1972·Archives of General Psychiatry·J P FeighnerR Munoz
May 1, 1972·The American Journal of Psychiatry·D L Murphy, R Weiss
Jun 1, 1971·Archives of General Psychiatry·D S RobinsonD Sylwester


Jan 1, 1987·European Archives of Psychiatry and Neurological Sciences·A FleissnerB Fuisting
May 20, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·K M SummersM Sandler
Nov 15, 1985·Clinica Chimica Acta; International Journal of Clinical Chemistry·K M SummersI W Craig
Jan 1, 1984·Journal of Psychiatric Research·K H TachikiF J Hullett
Jan 1, 1984·Journal of Psychiatric Research·G MuscettolaC P Giannini
Jan 1, 1987·Journal of Psychiatric Research·B Bondy, M Ackenheil
Jul 1, 1986·Pharmacology, Biochemistry, and Behavior·G Gianutsos, S Chute
Mar 1, 1982·Journal of Affective Disorders·T R NormanG D Burrows
Feb 1, 1983·Journal of Affective Disorders·M T Abou-Saleh
Jan 1, 1987·Journal of Affective Disorders·R R CroweA M Persico
Oct 1, 1979·Psychiatry Research·R D KobesR J Wyatt
Jul 1, 1980·Psychiatry Research·X O BreakefieldE S Gershon
Dec 1, 1980·Psychiatry Research·C J FowlerL Oreland
Dec 1, 1980·Psychiatry Research·M BaronR Perlman
May 1, 1980·Psychiatry Research·L E DeLisiR J Wyatt
Aug 1, 1982·Psychiatry Research·M DuncavageH Y Meltzer
Dec 1, 1982·Psychiatry Research·J RiceE G Shaskan
Aug 1, 1984·Psychiatry Research·E GillerB Sherman
Mar 1, 1984·Psychiatry Research·M BaronJ Kane
Jun 1, 1985·Psychiatry Research·M BaronR Gruen
Feb 1, 1987·Psychiatry Research·R YehudaJ S Meyer
Aug 1, 1991·Psychiatry Research·D Mück-SelerZ Deanović
Dec 1, 1994·General Pharmacology·P H Yu
Sep 1, 1992·Schizophrenia Research·M A Marcolin, J M Davis
Mar 22, 2003·Schizophrenia Research·Erik G JönssonGöran C Sedvall
Mar 1, 1981·Journal of Clinical Pathology·M SandlerV Glover
Dec 1, 1984·Journal of Pharmacological Methods·E NissinenP Männistö
Nov 1, 2013·World Journal of Psychiatry·Eyal Asor, Dorit Ben-Shachar
Oct 1, 1987·The British Journal of Psychiatry : the Journal of Mental Science·F OwenM Poulter
Jun 1, 1983·The British Journal of Psychiatry : the Journal of Mental Science·M A ReveleyR M Murray

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