Platelet-rich plasma for resistant oral erosions of pemphigus vulgaris: A pilot study

Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society
Mohamed Hussein Medhat EL-KomyMarwah Adly Saleh

Abstract

Oral erosions and ulcers of pemphigus vulgaris (PV) are a debilitating condition that is usually difficult to treat. The wound healing properties of platelet-rich plasma (PRP) encouraged us to evaluate its usefulness in treatment of non-healing oral PV lesions. Seven patients with chronic oral PV, resistant to conventional therapy, were treated with weekly to monthly injections of PRP of affected mucosal membranes. All recruits reported improvement in pain and mastication and 6 of 7 patients had an improvement in pemphigus disease area index scores with PRP treatment. PRP injections seems to accelerate the healing process and decrease the pain and eating discomfort associated with the oral erosions and ulcers induced by PV.

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Citations

Sep 26, 2019·Frontiers in Cardiovascular Medicine·Faez Saleh Al-HamedFaleh Tamimi
May 28, 2019·Frontiers in Immunology·Kentaro IzumiRalf J Ludwig
Dec 6, 2019·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Emily F ColeRon J Feldman
Mar 30, 2017·American Journal of Clinical Dermatology·Laura PiñasEduardo Anitua

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