Platelet-rich plasma injections for carpal tunnel syndrome: a systematic and comprehensive review

European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie
Michael-Alexander MalahiasGeorge C Babis

Abstract

A series of clinical trials focused on the use of ultrasound-guided platelet-rich plasma (PRP) infusions for the treatment of patients with carpal tunnel syndrome (CTS) were published over the last few years. However, the role of PRP for CTS remains unclear. We performed a systematic review according to Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Two reviewers independently conducted the search using multiple databases: MEDLINE/PubMed, SCOPUS, Cochrane Database, and Web of Science. These databases were searched using terms "platelet" AND "rich" AND "plasma" AND "carpal" AND "tunnel". To maximize the search, backward chaining of references from retrieved papers was also undertaken. From the initial 19 studies, only five met our eligibility criteria. These articles included one randomized controlled double-blind study, one randomized controlled single-blind study, one randomized controlled non-blind study, one case-control study, and one case report. The vast majority of the included studies supported that PRP infusion improved the clinical condition of the patients and that PRP infusion was beneficial for patients with mild-to-moderate CTS. Therefore, PRP seems to be an interesting alternative ...Continue Reading

References

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Citations

Nov 13, 2019·European Radiology·Luca Maria SconfienzaUNKNOWN Ultrasound and Interventional Subcommittees of the European Society of Musculoskeletal Radiology (ESSR)
Aug 3, 2019·Current Pain and Headache Reports·Ivan UritsOmar Viswanath
Jun 10, 2021·International Journal of Clinical Practice·Yu-Ping ShenYung-Tsan Wu

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