Platelet size and left ventricular hypertrophy in hypertensive patients over 50 years of age

European Journal of Clinical Investigation
A ScuteriV Marigliano

Abstract

Both mean platelet volume (MPV) and left ventricular hypertrophy have been described as associated with increased risk for vascular events. Seventy-six hypertensive patients (37 M and 39 F) over 50 years of age were studied. They were divided into subgroups according to the presence of left ventricular hypertrophy (LVH = LV mass index > 125 g m-2, when LV mass was assessed by M-mode echocardiography according to Penn's Convention). MPV was 3% higher in hypertensive patients with LVH compared with those without LVH (P > 0.05) and it was associated with the occurrence of LVH (chi-square = 8.44, P = 0.042). MPV significantly correlated with left ventricular mass index (r = 0.298, P = 0.004) and interventricular septum thickness (r = 0.231, P = 0.022). Both correlations remained significant after adjustment for age, blood pressure and glycaemia. MPV seemed to be associated with increased left ventricular mass and interventricular septum thickness in middle-aged to elderly hypertensive patients.

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Citations

Jul 8, 2015·Clinical and Experimental Hypertension : CHE·Satoshi KurisuYasuki Kihara
Nov 26, 2009·Blood Pressure·Serkan OrduIsmail Erden
Oct 24, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Hamdi PusurogluAydin Yildirim
Jun 12, 1999·Journal of the American Geriatrics Society·A ScuteriV Marigliano
May 12, 2012·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Serkan BulurHakan Ozhan

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