Platelet-to-lymphocyte ratio is a marker of poor prognosis in patients with diabetes mellitus and ST-elevation myocardial infarction

Biomarkers in Medicine
Bartosz HudzikLech Poloński

Abstract

Platelet-to-lymphocyte ratio (PLR) has emerged as a strong marker of worse outcomes. We determined the association between PLR and clinical outcomes in patients with diabetes mellitus and ST-elevation myocardial infarction. Five hundred and twenty three patients were enrolled. Low PLR (group 1, n = 349) was defined as ≤ 124 and high PLR (group 2, n = 174) as >124. In-hospital and 1-year mortality was higher in group 2. Receiver operating characteristic analysis revealed moderate diagnostic value in predicting in-hospital (PLR cut-off >155) and long-term (PLR cut-off >146) death. PLR remained an independent risk factor of early and late mortality. PLR proved to have good prognostic value for in-hospital and late mortality. PLR cut-off value for predicting in-hospital mortality was higher to that predicting late mortality. PLR remained an independent risk factor early and late mortality.

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Citations

Jan 14, 2016·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Ahmet SahbazUlku Ozmen
Dec 29, 2015·The Kaohsiung Journal of Medical Sciences·Cemil ZencirHasan Gungor
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May 8, 2018·Frontiers in Oncology·Preeti Kanikarla-MarieDavid G Menter
Mar 5, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Wenwen ChenFeixia Shen

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