PMID: 3764332Jul 1, 1986Paper

Platelet volume analysis in thrombocytopenia in relation to bleeding tendency

Scandinavian Journal of Haematology
J Van der LelieA K Von dem Borne

Abstract

It has been shown that large platelets are hemostatically more active than the smaller ones. We therefore studied the relationship between the mean platelet volume and the percentage of micro- and mega-thrombocytes measured by a Coulter counter S plus II, and the bleeding tendency in 57 unselected patients with a platelet count below 50 X 10(9)/l. We found no significant differences for any of these parameters between patients without and those with mild or severe bleeding tendency. This also held true when patients with a possible platelet dysfunction or with coagulation abnormalities were excluded. We conclude that platelet volume analysis in unselected patients with severe thrombocytopenia is not helpful in the prediction of their risk of bleeding.

References

Jan 1, 1979·Clinical and Laboratory Haematology·R M RowanG A McDonald
Aug 1, 1977·Thrombosis Research·H Johnsson, P M Niklasson
Jan 7, 1971·The New England Journal of Medicine·S K GargS Karpatkin
Aug 7, 1982·British Medical Journal·A EldorS Penchas

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Citations

Jul 13, 2000·Critical Care Medicine·S VanderschuerenH Bobbaers
Jan 10, 2014·European Journal of Haematology·Pernille J VinholtMads Nybo
Aug 3, 2021·Journal of Thrombosis and Haemostasis : JTH·Wobke E M van DijkKarin P M van Galen

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