Platelets and their biomimetics for regenerative medicine and cancer therapies

Journal of Materials Chemistry. B, Materials for Biology and Medicine
Zhenhua LiKe Cheng

Abstract

Platelets, circulating blood cells derived from megakaryocytes, play a key role in various physical activities, including coagulation, hemostasis, the body's innate immune response, and cancer metastasis. By taking advantage of their key traits, researchers have developed strategies to exploit platelets and platelet-mimicking nanoassemblies to treat a number of conditions, including wounds, cancers, and bacterial infections. Compared to traditional polymer, lipsosome, and inorganic nanoparticles-based delivery systems, platelets and platelet-mimicking vehicles hold many advantages. Among these are their enhanced circulation time, their large volumes and surface areas for drug loading or conjugation, and their inherent ability to target some diseases. In this review, we will highlight the recent progress made in the development of disease-targeting platelets- and platelet-mimicking-vehicles as therapeutic platforms.

References

Nov 1, 1992·American Journal of Clinical Pathology·M HoffmanH R Roberts
Feb 5, 2004·Journal of Theoretical Biology·Markus R OwenClaire E Lewis
May 24, 2007·Archives of Facial Plastic Surgery·David B HomTrevor C Huang
Nov 26, 2009·The Journal of International Medical Research·Tomaz VelnarV Smrkolj
Feb 4, 2010·ACS Nano·Hao ChengDaniel G Anderson
Jul 14, 2010·Advanced Drug Delivery Reviews·Qizhen Shi, Robert R Montgomery
Jun 22, 2011·Proceedings of the National Academy of Sciences of the United States of America·Che-Ming J HuLiangfang Zhang
Jul 27, 2012·Therapeutic Delivery·Carmen Gutiérrez MillánJosé M Lanao
Feb 21, 2013·Molecular Therapy : the Journal of the American Society of Gene Therapy·Cor Hj LamersJan W Gratama
Jun 7, 2013·Pharmaceutical Research·Sounik SarkarAnjan Kr Dasgupta
Dec 20, 2013·Pakistan Journal of Medical Sciences·Muhammad Saboor Moinuddin
Jan 30, 2014·Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur̈ Transfusionsmedizin Und Immunham̈atologie·Agnieszka Wieczorek, Lutz Uharek
Feb 1, 2014·Biomaterials·Isabella PallottaAlessandra Balduini
Apr 4, 2014·Cancer Metastasis Reviews·David G MenterKenneth V Honn
Aug 1, 2015·Therapeutic Delivery·Carlos H VillaVladimir R Muzykantov
Sep 12, 2015·International Journal of Cancer. Journal International Du Cancer·Nailin Li
Sep 17, 2015·Nature·Che-Ming J HuLiangfang Zhang
Sep 30, 2015·Advanced Materials·Quanyin HuZhen Gu
Dec 20, 2015·British Journal of Haematology·Katie L LannanSherry L Spinelli
Mar 5, 2016·Chemical Society Reviews·Anne-Marie Caminade
Mar 13, 2016·Advanced Materials·Lang RaoXing-Zhong Zhao
Mar 19, 2016·Advanced Healthcare Materials·Dafeng ChuZhenjia Wang
May 4, 2016·Advanced Drug Delivery Reviews·Jennifer I HareSimon T Barry
May 18, 2016·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Yu-Wen WuThierry Burnouf
Oct 27, 2016·Advanced Healthcare Materials·Bill ChengPatrick C H Hsieh
Sep 16, 2016·Advanced Materials·Huiping SunYaping Li
Oct 11, 2016·Chemical Society Reviews·N GrimaldiN Ventosa
Oct 30, 2016·Expert Opinion on Drug Delivery·Vivek AgrahariAshim K Mitra
Jan 25, 2017·ACS Applied Materials & Interfaces·Min GaoZhuang Liu
Feb 16, 2017·Advanced Materials·Diana DehainiLiangfang Zhang
Jul 20, 2017·Chemical Society Reviews·Giacomo ReinaMaurizio Prato
Sep 18, 2017·Drug Discovery Today·Thierry BurnoufHadi Goubran

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Citations

Dec 14, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Sen YeChun-Jian Li
Jun 5, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Caiyun ZhengTingli Lu
Aug 28, 2020·Expert Opinion on Drug Delivery·Claire H MastersonJohn G Laffey
Mar 3, 2020·Frontiers in Cell and Developmental Biology·Chengming FanWuqiang Zhu
Apr 8, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Mengjun ZhangDawei Chen
May 16, 2020·Frontiers in Bioengineering and Biotechnology·Tingting LiYiyao Liu
Oct 7, 2020·Science Robotics·Songsong TangJoseph Wang
Nov 24, 2020·Chemical Society Reviews·Guo-Feng LuoXian-Zheng Zhang
Dec 11, 2020·Journal of Controlled Release : Official Journal of the Controlled Release Society·Adrija JhaSrinivas Mutalik
Dec 29, 2020·International Journal of Nanomedicine·Wenjing PeiChengcheng Niu
Sep 11, 2020·Journal of Controlled Release : Official Journal of the Controlled Release Society·Pratigyan DashMamoni Dash
May 29, 2021·International Journal of Nanomedicine·Sasmita SamalMamoni Dash
Jun 22, 2021·Frontiers in Bioengineering and Biotechnology·Mira ChingaleKe Huang
Aug 10, 2021·Advanced Drug Delivery Reviews·Melgious Jin Yan AngXiaogang Liu
Apr 13, 2019·Accounts of Chemical Research·Zhaowei ChenZhen Gu
Jan 16, 2021·ACS Applied Materials & Interfaces·Lin LiHaitao Ran

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Methods Mentioned

BETA
Fluorescence
electrophoresis
dot blot

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