Platelets in inflammation and atherogenesis

Frontiers in Immunology
Henry M NordingHarald Langer

Abstract

Platelets contribute to processes beyond thrombus formation and may play a so far underestimated role as an immune cell in various circumstances. This review outlines immune functions of platelets in host defense, but also how they may contribute to mechanisms of infectious diseases. A particular emphasis is placed on the interaction of platelets with other immune cells. Furthermore, this article outlines the features of atherosclerosis as an inflammatory vascular disease highlighting the role of platelet crosstalk with cellular and soluble factors involved in atheroprogression. Understanding, how platelets influence these processes of vascular remodeling will shed light on their role for tissue homeostasis beyond intravascular thrombosis. Finally, translational implications of platelet-mediated inflammation in atherosclerosis are discussed.

References

Aug 12, 1994·Science·E Kopp, S Ghosh
Nov 1, 1995·European Journal of Clinical Investigation·M GawazK Werdan
Feb 7, 1998·The Journal of Experimental Medicine·T G DiacovoU H von Andrian
Jul 19, 2000·The Journal of Experimental Medicine·D I SimonJ A López
Feb 7, 2001·Circulation·P M RidkerN Rifai
Aug 8, 2001·The Journal of Cell Biology·S LindemannA S Weyrich
Mar 6, 2002·Circulation·Peter LibbyAttilio Maseri
Mar 13, 2002·Circulation·Johann W AuerBernd Eber
Jun 29, 2002·The American Journal of Cardiology·Freek W A Verheugt, Bernard J Gersh
Oct 9, 2002·The Journal of Experimental Medicine·Steffen MassbergMeinrad Gawaz
Dec 14, 2002·Blood·Peter C Burger, Denisa D Wagner
Oct 7, 2003·Nature Medicine·Alexandra MoersStefan Offermanns
Dec 12, 2003·The New England Journal of Medicine·Frank D KolodgieRenu Virmani
Jan 31, 2004·Cellular Signalling·Jin-Sheng HuangGuy C Le Breton
Feb 3, 2004·Current Pharmaceutical Design·Juan AcostaJose Halperin
Feb 7, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Silvio DaneseClaudio Fiocchi
Apr 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Masao HagiharaShinya Goto
Jul 9, 2004·The Journal of Experimental Medicine·Mark J Paul-ClarkDerek W Gilroy
Sep 24, 2004·Thrombosis Research·Masaaki Moroi, Stephanie M Jung
Feb 25, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Chao Yan LiuGian Paolo Visentin
May 19, 2005·Journal of Leukocyte Biology·Bennett D ElzeyTimothy L Ratliff
Jun 11, 2005·Arteriosclerosis, Thrombosis, and Vascular Biology·Gourab BhattacharjeeThomas S Edgington
Jul 23, 2005·Arteriosclerosis, Thrombosis, and Vascular Biology·Renu VirmaniJagat Narula
Aug 17, 2005·Journal of Thrombosis and Haemostasis : JTH·Y OzakiM C Berndt
Nov 1, 2005·Nature Medicine·Matteo IannaconeLuca G Guidotti
Dec 3, 2005·The Journal of Clinical Investigation·Meinrad GawazAndreas E May

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Citations

Jan 14, 2016·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Ahmet SahbazUlku Ozmen
Dec 17, 2015·Scientific Reports·I Re LeeJi Hong Kim
Jan 14, 2016·British Journal of Pharmacology·Sven Nylander, Rainer Schulz
Jun 20, 2015·Frontiers in Immunology·Olivier Garraud
Oct 26, 2016·Frontiers in Immunology·Changjun YinAndreas J R Habenicht
Oct 19, 2016·International Journal of Molecular Sciences·Susann PankratzKerstin Göbel
Dec 2, 2015·Scientific Reports·Yanjia ChenWei Jin
Jan 7, 2017·Scientific Reports·Marina Panova-NoevaPhilipp S Wild
Feb 9, 2017·Blood·Melinda D WuJonathan R Lindner
Mar 14, 2018·Platelets·Hind Hamzeh-CognasseFabrice Cognasse
Sep 12, 2017·European Journal of Heart Failure·Yingying ZhangHarald F Langer
Jun 21, 2018·Expert Opinion on Pharmacotherapy·Paschalis SteiropoulosNikolaos Papanas
Jul 19, 2018·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Kostas ArchontogeorgisPaschalis Steiropoulos
Feb 6, 2017·Circulation Research·Xiaoming HuFrank M Faraci
Apr 22, 2016·Circulation. Cardiovascular Genetics·Wei WangCarrie L Welch
Mar 25, 2019·Cardiovascular Research·Melanie ZieglerKarlheinz Peter
Apr 30, 2019·Journal of Thrombosis and Haemostasis : JTH·Maryam F SalamahSakthivel Vaiyapuri
Apr 30, 2019·Angiology·Alparslan Kurtul, Ender Ornek
Sep 29, 2019·Clinical Hemorheology and Microcirculation·Helen Ullrich, Tommaso Gori
Aug 14, 2015·Current Opinion in Lipidology·Maiwand AhmadseiNorbert Gerdes
May 11, 2017·Journal of Lipid Research·Marco De GiorgiSimon C Robson
Dec 6, 2018·International Journal of Molecular Sciences·Tommaso Gori
Apr 3, 2019·International Journal of Molecular Sciences·Johannes M BreussPavel Uhrin
Feb 6, 2017·The Journal of Obstetrics and Gynaecology Research·Cift TayfurOzdemir Orcun
Feb 20, 2019·International Journal of Molecular Sciences·Ruben EsseRita Castro
Mar 7, 2020·Nanoscale Horizons : the Home for Rapid Reports of Exceptional Significance in Nanoscience and Nanotechnolgy·Joon Ho ParkLiangfang Zhang
Oct 1, 2020·Food Science & Nutrition·Arshad MehmoodChengtao Wang

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