Pleiotropic effects of juvenile hormone in ant queens and the escape from the reproduction-immunocompetence trade-off

Proceedings. Biological Sciences
Tobias PammingerWilliam O H Hughes

Abstract

The ubiquitous trade-off between survival and costly reproduction is one of the most fundamental constraints governing life-history evolution. In numerous animals, gonadotropic hormones antagonistically suppressing immunocompetence cause this trade-off. The queens of many social insects defy the reproduction-survival trade-off, achieving both an extraordinarily long life and high reproductive output, but how they achieve this is unknown. Here we show experimentally, by integrating quantification of gene expression, physiology and behaviour, that the long-lived queens of the ant Lasius niger have escaped the reproduction-immunocompetence trade-off by decoupling the effects of a key endocrine regulator of fertility and immunocompetence in solitary insects, juvenile hormone (JH). This modification of the regulatory architecture enables queens to sustain a high reproductive output without elevated JH titres and suppressed immunocompetence, providing an escape from the reproduction-immunocompetence trade-off that may contribute to the extraordinary lifespan of many social insect queens.

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Citations

Oct 11, 2016·Current Opinion in Insect Science·Marisa A Rodrigues, Thomas Flatt
Oct 11, 2016·Current Opinion in Insect Science·Jane de Verges, Volker Nehring
Nov 22, 2016·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Philip A DowningAshleigh S Griffin
Dec 5, 2019·The Journal of the Acoustical Society of America·Neofytos KaplanisSøren Holdt Jensen
Jul 14, 2017·Proceedings. Biological Sciences·Pierre BlacherAndrew F G Bourke
Oct 27, 2016·Evolution; International Journal of Organic Evolution·Tobias Pamminger, William O H Hughes
Feb 20, 2021·Genes & Development·Comzit OpachaloemphanClaude Desplan
Jun 12, 2019·Hormones and Behavior·Elizabeth A TibbettsMarlene Goubault

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