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Pleiotropic genes in psychiatry: Calcium channels and the stress-related FKBP5 gene in antidepressant resistance

Progress in Neuro-psychopharmacology & Biological Psychiatry

Oct 11, 2017

C FabbriA Serretti

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Abstract

A candidate gene and a genome-wide approach were combined to study the pharmacogenetics of antidepressant response and resistance. Investigated genes were selected on the basis of pleiotropic effect across psychiatric phenotypes in previous genome-wide association studies and involvemen...read more

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Biological Markers
STAR protein, human
Gene Polymorphism
Genome-Wide Association Study
Study
Biochemical Pathway
Metabotropic glutamate receptor 7
Genome
Genes
Involutional Paraphrenia
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Pleiotropic genes in psychiatry: Calcium channels and the stress-related FKBP5 gene in antidepressant resistance

Progress in Neuro-psychopharmacology & Biological Psychiatry

Oct 11, 2017

C FabbriA Serretti

PMID: 28989100

DOI: 10.1016/j.pnpbp.2017.10.005

Abstract

A candidate gene and a genome-wide approach were combined to study the pharmacogenetics of antidepressant response and resistance. Investigated genes were selected on the basis of pleiotropic effect across psychiatric phenotypes in previous genome-wide association studies and involvemen...read more

Mentioned in this Paper

Biological Markers
STAR protein, human
Gene Polymorphism
Genome-Wide Association Study
Study
Biochemical Pathway
Metabotropic glutamate receptor 7
Genome
Genes
Involutional Paraphrenia

Feeds With Similar Papers

Selective Ion Transport in Channels & Pumps

Ion channels and pumps are central to a number of cell functions, including membrane excitability and synaptic transmission. With sophisticated imaging, these channels and pumps have been characterized as selective for the ions, sodium, potassium chloride and calcium. Here is the latest research on selection ion transport in channels and pumps.

Depression

Depression, also known as major depressive disorder, is a medical condition associated with negative emotional, behavioural, and cognitive symptoms. Here is the latest research on this mood disorder.

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Paper Details
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  • Citations4
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations4
1

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