Pleural metastatic disease from glioblastoma multiforme

Journal of Thoracic Imaging
Michael B GotwayRoss M Bremner

Abstract

Glioblastoma multiforme (GBM) is a malignant primary brain neoplasm with poor survival. Extracranial GBM dissemination is very uncommon, but is increasingly being recognized. The imaging features of metastatic pleural GBM are not specific for a primary central nervous system neoplasm. In this case, extracranial GBM metastases presented as circumscribed posterobasal pleural nodules. Diagnoses may be established with percutaneous or thoracoscopic biopsy. Radiologists should be familiar with the possibility of the extracranial spread of GBM because as therapeutic improvements provide increased local control of the primary tumor, improving patient survival, extracranial spread of disease will be increasingly encountered on thoracoabdominal imaging studies.

Citations

Sep 15, 2010·Cancer Metastasis Reviews·Leanne C Huysentruyt, Thomas N Seyfried
Aug 13, 2011·ASN Neuro·Leanne C HuysentruytThomas N Seyfried
Dec 15, 2012·Critical Reviews in Oncogenesis·Thomas N Seyfried, Leanne C Huysentruyt
Sep 26, 2013·Advanced Drug Delivery Reviews·Yu ChengMaciej S Lesniak
Feb 26, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jackson D HamiltonChristiane Matuschek
Jun 15, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stefan S SchönsteinerRegine Mayer-Steinacker
Feb 22, 2014·Journal of Neuro-oncology·Daniel Thomas Ginat, Pamela W Schaefer

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