Pneumatosis cystoides intestinalis of the ascending colon related to acarbose treatment: a case report.

Journal of Medical Case Reports
Yilin VogelBernhard F Henning

Abstract

Pneumatosis cystoides intestinalis is characterized by the presence of multiple gas-filled cysts in the intestinal wall, the submucosa and/or subserosa of the intestine. The term pneumatosis cystoides coli is synonymous with pneumatosis cystoides intestinalis when the disorder is limited to the colon. It is a secondary finding caused by a wide variety of underlying gastrointestinal or extragastrointestinal diseases but rarely occurs in the course of treatment with an alpha-glucosidase inhibitor. This is the first report of pneumatosis cystoides intestinalis after 12 years of treatment with the alpha-glucosidase inhibitor acarbose. A 65-year-old Caucasian German woman was referred to our hospital for hemicolectomy. She had been treated for type 2 diabetes mellitus with an alpha-glucosidase inhibitor (acarbose, 150 mg daily) for 12 years. Three months before referral, she had complained of left abdominal pain. 'Polyposis coli' in the ascending colon and diverticulosis were diagnosed. Colonoscopy and computed tomography scans of the abdomen were repeated and revealed pneumatosis cystoides coli located in the ascending colon, whereas diverticulosis of the sigmoid colon was confirmed. Histological examination of a biopsy specimen on...Continue Reading

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Citations

Aug 6, 2010·Internal Medicine·Kuniyuki KojimaHiroshi Fukui
Dec 1, 2012·Familial Cancer·Maurizio Ponz de LeonElio Jovine
Jul 13, 2013·The Journal of Surgical Research·Murad Bani HaniSteven C Cunningham
Dec 15, 2015·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Dorota Ksiadzyna, Amado Salvador Peña
Jul 27, 2016·BJR Case Reports·Claudia SassiGiuseppe Battista
Mar 28, 2021·Clinical Journal of Gastroenterology·Justin RoyIan Schreibman

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Methods Mentioned

BETA
biopsy
hysterectomy
X-ray

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