Pneumococcal vaccination rates in immunocompromised patients-A cohort study based on claims data from more than 200,000 patients in Germany

PloS One
Niklas SchmedtDennis Häckl

Abstract

The German Committee on Vaccination recommends pneumococcal vaccination for infants, seniors 60+ years and patients at risk with defined underlying diseases. Aim of this study was to assess the pneumococcal vaccination rate (pnc-VR) in patients with certain incident inherited or acquired immunodeficiency or immunosuppression and to understand who vaccinates these patients who are particularly at high risk to develop a pneumococcal infection. We conducted a cohort study in patients aged 2 years or older, with a first episode of a "high-risk" condition between January 2013 and December 2014 based on a representative sample of German claims data. Pnc-VR was calculated as the proportion of patients receiving any pneumococcal vaccine within two years after first episode of "high-risk" condition. Further analyses cover pnc-VR stratified by high risk conditions and region, time to vaccination, and physician specialty administering the pneumococcal vaccination. The study population comprised 204,088 incident "high-risk" patients (56% female). The overall pnc-VR within two years was 4.4% (95%-confidence interval: 4.3%-4.5%). Within specific high-risk conditions, we found the highest vaccination rate of 11.5% (10.1%-13.0%) among patients...Continue Reading

References

Jun 22, 2013·International Journal of Methods in Psychiatric Research·Frank JacobiHans-Ulrich Wittchen
Oct 31, 2015·BMC Infectious Diseases·Stephen I PeltonDerek Weycker
Nov 5, 2015·Pharmacoepidemiology and Drug Safety·Frank Andersohn, Jochen Walker
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Citations

May 21, 2020·Human Vaccines & Immunotherapeutics·Ignacio Hernández-García, Carlos Aibar-Remón
Mar 12, 2020·Open Forum Infectious Diseases·Siegbert RiegChristian Theilacker
Jan 30, 2021·NPJ Primary Care Respiratory Medicine·Jasmin BossertMichel Wensing
Feb 27, 2021·Journal of Intensive Care Medicine·Marco KrasseltOlga Seifert
Jun 3, 2021·Vaccines·Claire FronemanRicardo J José
Jun 16, 2021·PloS One·Christian TheilackerJulia Schiffner-Rohe

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