Pneumococci: immunology of the innate host response

Respirology : Official Journal of the Asian Pacific Society of Respirology
Gavin K Paterson, Carlos J Orihuela

Abstract

Despite the development of vaccines and antibiotics, Streptococcus pneumoniae (the pneumococcus) continues to be a major cause of human morbidity and mortality throughout the world. In recent years our understanding of how the host innate immune system recognizes and responds to pneumococcal infection has advanced significantly. Herein, we highlight some of the key features of the innate response to the pneumococcus.

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Related Concepts

Complement Activation
Resistance, Natural
Neutrophil Band Cells
Pneumococcal Infections
Streptococcal Pneumonia
Cytokine
Pneumovax
Scavenger Receptors, Macrophage
Toll-like receptors
Antibiotics

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