PMID: 11924750Apr 2, 2002Paper

Pneumonia-associated acute glomerulonephritis

Clinical Nephrology
T SrivastavaU S Alon

Abstract

Post-infectious glomerulonephritis typically occurs 7-14days after an infection. However, in several children we observed acute glomerulonephritis (AGN) to develop concurrently with pneumonia. The objective of the study was to delineate the clinical course and outcome of pneumonia-associated AGN. The hospital database was searched from 1984 - 1999 for c+hildren admitted with both acute pneumonia and AGN, each diagnosis having been made within 72 hours of each other. 11 boys, age 3.8- 12.7 years, were identified. Ten children had lobar pneumonia and I had an interstitial infiltrate. All responded to antibiotic therapy with resolution of fever and respiratory symptoms. Only I child developed an empyema. The mean +/- SD hospital stay was 5.9 +/- 3.9 days. All patients had an abnormal urinalysis with hematuria (gross hematuria in 5), proteinuria and cellular casts. At presentation, 7 children had a serum creatinine > 1.0 mg/dl and creatinine clearance < or = 80 ml/min/1.73 m2; in all, serum creatinine returned to normal and the creatinine clearance was > 80 ml! min/1.73 m2 on follow-up. Nine of the 11 children had a low serum complement C3, 3 of whom also had low complement C4. Anti-streptolysin-O (ASO) titers were elevated in all ...Continue Reading

Citations

Apr 23, 2009·Nature Reviews. Nephrology·Talerngsak KanjanabuchSomchai Eiam-Ong
Dec 23, 2003·The Pediatric Infectious Disease Journal·Ekaterini SiomouZoe L Papadopoulou
Mar 17, 2009·Pediatric Emergency Care·Andrew FretzayasMaria Moustaki
Aug 24, 2013·Case Reports in Medicine·Giovanna VitalitiPiero Pavone
Mar 1, 2013·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Helena BedanovaPetr Nemec
Jul 5, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·María del Carmen LasoEnrique Casanueva
Aug 12, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fernando Carceller LechónJose Luis Écija Peiró
Sep 24, 2008·Néphrologie & thérapeutique·Arnaud GarnierGeorges Deschênes
Oct 19, 2013·Pediatrics International : Official Journal of the Japan Pediatric Society·Satoshi HibinoKazuo Itabashi
Apr 22, 2015·Indian Journal of Pediatrics·Kuralvanan GunasekaranAjith Prabhu Kumar
Jan 20, 2019·Clinical Pediatrics·Mafalda CascaisAntónio Jorge Correia
Dec 15, 2020·Pediatric Pulmonology·Ugur B BalkanciNadir Demirel

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