Pneumonia due to varicella-zoster virus reinfection in a renal transplant recipient

Transplantation Proceedings
A SatoY Takahashi

Abstract

Varicella pneumonia is one of the serious complications of primary varicella zoster virus (VZV) infection in adults. A 36-year-old woman with end-stage renal disease underwent renal transplantation from a living donor in 1998, receiving immunosuppressive treatment with cyclosporine, mycophenolate mofetil, and methylprednisolone. She had a history of VZV infection during childhood. The patient developed an intractable cough on December 10, 2006, but there were no abnormalities in the laboratory data or chest radiograph for several weeks. On January 1, 2007, she was admitted to our hospital with cutaneous vesicles covering the entire body. We learnt that when her symptoms developed, her son was diagnosed with varicella. The chest radiograph at this stage showed a diffuse miliary pattern in the entire lung field. We started intravenous administration of acyclovir. VZV antigen was detected in the cutaneous lesions and VZV antibody in the serum after the start of these treatments, so we continued to administer acyclovir for 18 days. The cutaneous lesions healed and the pneumonia improved based on the chest radiograph. She was discharged from the hospital on January 19, 2007. In conclusion, this report documents VZV reinfection in a ...Continue Reading

References

Sep 1, 1996·Infectious Disease Clinics of North America·J I Cohen
Jun 5, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Claire A Scanlon-KohlroserJeffrey S Stoff
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Nov 14, 2006·Transplantation Proceedings·A Rodriguez-MorenoA Barrientos

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Citations

Jan 15, 2013·Current Treatment Options in Neurology·John E Greenlee
Oct 26, 2010·Transplantation Proceedings·I HoyoA Moreno
Apr 2, 2015·Journal of Equine Science·Atsushi Hiraga, Shigeru Sugano
Jan 14, 2016·Archives of Pathology & Laboratory Medicine·Megan L Troxell, Christian Lanciault
Jul 26, 2018·BMC Nephrology·Chong Yau OngLian Leng Low

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