PMID: 7086585Jun 1, 1982Paper

Pneumothorax in cystic fibrosis: management and outcome

The Journal of Pediatrics
F J McLaughlinH Shwachman

Abstract

We reviewed our experience over the past 12 years to determine the best method of management, to determine the morbidity and the physiologic outcome of medical vs surgical treatment of pneumothorax complicating CF, and to assess the influence of age, sex, and Shwachman scores on survival. Sixty-five patients, ages ranging from 5 to 32 years (mean 18 years). Shwachman scores ranging from 25 to 87 (mean 57), and a male-female ratio of 1:1, experienced 170 pneumothoraces, 93 first episodes, and 77 recurrences, requiring 211 trials of management. All methods of management except needle aspiration resulted in a fair rate of resolution (70 to 100%), but recurrence rates were high for observation (60%), needle aspiration (79%), trocar thoracotomy (63%), tetracycline sclerosis (86%), and silver nitrate sclerosis (43%). The recurrence rates were 12.5% for quinacrine sclerosis and 0% for parietal pleurectomy. Quinacrine sclerosis and parietal pleurectomy were the most effective methods of management. There was no significant difference in pulmonary function before pneumothorax and after pleural sclerosis or parietal pleurectomy. Age, sex, and severity of pulmonary disease were all independent variables influencing prognosis. Severity of ...Continue Reading

References

Dec 1, 1968·American Journal of Diseases of Children·M I LifschitzR H Wylie
Mar 1, 1970·Thorax·P F Mitchell-Heggs, J C Batten

Citations

Jan 1, 1994·Lung·M R ByeL M Quittell
May 1, 1987·The American Journal of Medicine·N N HuangS Fiel
Sep 9, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Matilde RollaFederico Venuta
Oct 21, 1999·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·O A MinaiS Kesten
Apr 28, 2009·Respiratory Care·Patrick A Flume
Feb 1, 1989·Chest·S H LoringM E Wohl
Aug 16, 2005·Chest·Patrick A FlumeLeslie L Clark
Aug 5, 2009·Paediatric Respiratory Reviews·Paul D RobinsonSarath C Ranganathan
Dec 26, 2007·Seminars in Pediatric Surgery·Alex G Cuenca, Elizabeth A Beierle
Jul 1, 1987·Journal of Pediatric Surgery·M M OlsenR J Izant
Sep 1, 1984·The Journal of Pediatrics·F L JohnsonT R Callihan
Jul 5, 2016·Paediatric Respiratory Reviews·Robert W LordPeter J Barry
Apr 5, 2011·Current Opinion in Pulmonary Medicine·Patrick A Flume
Jan 27, 2019·American Journal of Respiratory and Critical Care Medicine·Philip M BooneBenjamin A Raby

Related Concepts

Teens
Pulmonary Cystic Fibrosis
Intubation
Visceral Pleura
Spontaneous Pneumothorax
Quinacrine, (S)-Isomer
Respiratory Function Tests
Retrospective Studies
Sclerosing Drugs
Silver Nitrate, Silver (2+) Salt (2: 1)

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.

Related Papers

The Annals of Thoracic Surgery
M L Spector, R C Stern
The Journal of the Royal College of Physicians of Edinburgh
A E Leitch, H C Rodgers
Medicine and Health, Rhode Island
M A Passero
© 2021 Meta ULC. All rights reserved