pO2 and pCO2 increment in post-dialyzer blood: the role of dialysate

Artificial Organs
K SombolosTaïsir A Natse

Abstract

Blood returning from a dialyzer during hemodialysis has a higher pO2 and pCO2 content than blood entering the dialyzer, and this has been attributed to the dialysate. The present study investigates this phenomenon. Acid-base and blood-gas parameters (pH, pO2, pCO2 and HCO3) were measured in three groups of stable chronic hemodialysis patients (A, B, and C) undergoing high-flux hemodialysis. In group A (n = 15), "arterial" (a) and "venous" (v) samples were withdrawn simultaneously before dialysis (samples A0), 5 min after circulation of the blood with the dialysate in the by-pass mode (samples A5), and 5 min after high-flux hemodialysis at a zero ultrafiltration rate (samples A10). In group B (n = 11) (a) and (v) samples were withdrawn simultaneously before dialysis (samples B0), 5 min after isolated-ultrafiltration with closed dialysate ports ("isolated-closed" ultrafiltration) (samples B5), and 5 min after high-flux hemodialysis at a zero ultrafiltration rate (samples B10). In group C (n = 14), after an initial arterial blood sample withdrawal before hemodialysis (sample C0), high-flux hemodialysis at a zero ultrafiltration rate was initiated. Five minutes later, blood and dialysate samples were withdrawn simultaneously from t...Continue Reading

References

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Citations

Dec 19, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Manish P PondaThomas H Hostetter
Jan 10, 2009·Artificial Organs·Simone Manca-Di-VillahermosaMassimo Taccone-Gallucci
Nov 19, 2014·TheScientificWorldJournal·María M Adeva-AndanyAlberto Domínguez-Montero
Dec 7, 2010·Néphrologie & thérapeutique·Thierry PetitclercJalel Hmida
Oct 18, 2015·Néphrologie & thérapeutique·Jan HavlinKarel Matousovic
May 6, 2015·Artificial Organs·Marco MaranoGiuseppe Iulianiello
Mar 14, 2008·Journal of Renal Care·Karen Latchford, Jan Cowperthwaite
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Nov 18, 2017·Seminars in Dialysis·Qi Qian
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