PMID: 9160027May 1, 1997Paper

Pointwise univariate linear regression of perimetric sensitivity against follow-up time in glaucoma

Ophthalmology
J M WildG E Trope

Abstract

The authors compared pointwise univariate linear regression (ULR) of sensitivity against follow-up as an indicator of visual field progression with that of the corresponding ULR of mean deviation (MD) and with the Glaucoma Change Probability (GCP) analysis. The authors determined the influence of the number and sequence of prior examinations on the slope of the pointwise function. Univariate linear regression was undertaken at each stimulus location on the arbitrarily assigned left eyes of 38 patients with glaucoma examined with the Humphrey Field Analyzer Programs 30-2 or 24-2 (stimulus size III, Humphrey Instruments Inc, San Leandro, CA). The mean age was 59.0 years (standard deviation [SD] = 12.9), the mean number of fields per patients was 12.0 (SD = 2.8), and the mean duration of follow-up was 6.0 years (SD = 1.6). Four patients showed statistically significant MD slopes. Of the 34 patients exhibiting a nonsignificant MD slope, 15 exhibited clusters of at least two contiguous progressing locations. Less than half of these locations were designated as progressing by GCP. The GCP detected less than one third of the locations considered progressing by ULR for the last six fields in the series: this was attributed to the nonli...Continue Reading

References

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Citations

Aug 27, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kouros Nouri-MahdaviJoseph Caprioli
Mar 29, 2002·Survey of Ophthalmology·Paul G D Spry, Chris A Johnson
Jun 6, 1998·Eye·A C Viswanathan, R A Hitchings
Jul 11, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·P G Spry, C A Johnson
Mar 2, 2002·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Paul G D SpryRichard A Harrad
Apr 26, 2002·The British Journal of Ophthalmology·S K Gardiner, D P Crabb
Dec 15, 2010·Archives of Ophthalmology·Paul H ArtesUNKNOWN Ocular Hypertension Treatment Study Group
Feb 17, 2015·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Luke X ChongAllison M McKendrick
Feb 18, 2004·Vision Research·Stuart K GardinerRoger A Hitchings
Jan 18, 2006·Vision Research·S K GardinerC A Johnson
Oct 25, 2016·Progress in Retinal and Eye Research·C Gustavo De MoraesLeonard A Levin

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