Polarity is destiny.

Cell
Liang Cai, Keith Mostov

Abstract

The GTPase Cdc42 specifies polarity in various biological processes. Kesavan et al. (2009) now demonstrate that Cdc42 also regulates epithelial cell polarity in the developing mouse pancreas, where it is required for tubule formation and maintenance. Furthermore, the polarization of epithelial tissue influences the differentiation of pancreatic progenitor cells, linking cell polarity to cell specification.

References

Jul 25, 2006·Nature Cell Biology·Yasutaka OhtaThomas P Stossel
Nov 17, 2009·Cell·Gokul KesavanHenrik Semb

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Citations

Apr 30, 2011·Histochemistry and Cell Biology·Silvia DoratiottoEzio Laconi
Mar 25, 2011·American Journal of Physiology. Renal Physiology·Zhiguo MaoAlbert C M Ong
Jan 27, 2010·The British Journal of Nutrition·Jenny EpsteinThomas T Macdonald

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