Polidocanol injection therapy for small-bowel hemangioma by using double-balloon endoscopy

Gastrointestinal Endoscopy
Atsushi IgawaKazuaki Chayama

Abstract

Small-bowel hemangioma is a rare disease that often causes active bleeding. The standard therapeutic method for small-bowel hemangioma is surgical resection. The aim of this study was to evaluate the usefulness of polidocanol injection (PDI) for small-bowel hemangiomas. This study included 12 patients with obscure GI bleeding (6 male; mean age 62 years) with 39 small-bowel hemangiomas; patients were treated with PDI by using double-balloon endoscopy (DBE). EUS with DBE was performed before PDI. The lesions were divided into 2 groups according to tumor size: Group A (size <10 mm; 20 lesions) and group B (size ≥10 mm; 19 lesions). The outcomes of PDI treatment for small-bowel hemangioma were evaluated between the 2 groups. Additionally, in order to standardize the amount of PDI injected, the total amount of polidocanol according to lesion size was calculated. There was no difference in the location of lesions and treatment times between the 2 groups. Group B had a significantly higher injection time per lesion (P < .05) and amount of polidocanol per lesion than group A (P < .01). Rebleeding occurred in only 1 case (8%). There were no adverse events related to PDI. The contribution ratio between the lesion size and amount of polid...Continue Reading

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Citations

Oct 16, 2016·Gastrointestinal Endoscopy·Huaijie Wang, Ya Gao
Mar 10, 2018·Current Opinion in Gastroenterology·Stefania Chetcuti Zammit, Reena Sidhu
Nov 17, 2017·Scandinavian Journal of Gastroenterology·Shanyu QinHaixing Jiang
Mar 8, 2019·Current Opinion in Gastroenterology·Reena Sidhu
Mar 8, 2019·Current Opinion in Gastroenterology·Jean Christophe SaurinMathieu Pioche
Apr 3, 2020·Internal Medicine·Taiki AoyamaShinji Nagata
Apr 6, 2019·Current Opinion in Gastroenterology·Reena Sidhu
Jul 24, 2018·Therapeutic Advances in Gastroenterology·Sayoko KuniharaKazuaki Chayama
Jan 1, 2019·World Journal of Gastrointestinal Oncology·Ping-Fang HuBin Shi
Mar 2, 2021·World Journal of Clinical Cases·Huan YaoGuo-Qing Shi
Apr 17, 2021·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Hirosato TamariKazuaki Chayama
Jul 9, 2021·Current Gastroenterology Reports·David WestrichChristine Boumitri

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