Polioencephalomalacia and Heart Failure Secondary to Presumptive Thiamine Deficiency, Hepatic Lipidosis, and Starvation in 2 Abandoned Siamese Cats

Veterinary Pathology
H AnholtA Britton

Abstract

Two 4-year-old spayed female Siamese cats were seized by the British Columbia Society for the Prevention of Cruelty to Animals after confinement to an abandoned housing unit without food for 9 weeks. One cat was found dead, and the second was euthanized within 24 hours due to neurologic deterioration despite therapy. Polioencephalomalacia of the caudal colliculus, hepatic lipidosis, cachexia, and congestive heart failure with cardiomyocyte atrophy were identified in both cats through postmortem examination and attributed to a prolonged period of starvation. Brain lesions were likely the result of thiamine deficiency (Chastek paralysis), which can be associated with both malnutrition and liver disease. This case highlights the importance of thiamine supplementation during realimentation of cats with hepatic lipidosis. Heart failure resulting from cachexia may have contributed to the death of the first cat and the morbidity of the second cat.

References

Nov 1, 1993·Journal of Veterinary Internal Medicine·S A CenterJ King
Jul 1, 1956·Journal of Comparative Pathology·K V JUBBH V COATES
Jan 4, 2005·The Veterinary Clinics of North America. Small Animal Practice·Sharon A Center
Aug 3, 2010·Journal of Feline Medicine and Surgery·Viktor PalusGiunio Bruto Cherubini

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