May 22, 2003

Polioencephalomalacia in captive harbour seals (Phoca vitulina)

Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine
P WohlseinM Böer


In a colony of 11 harbour seals (Phoca vitulina Linné 1758) two episodes of central nervous disorders occurred within 2 years causing fatalities in seven adult animals. Clinical signs comprised dyspnoea, anorexia, apathy, incoordination and lateral recumbency. Vitamin B complex therapy was successful once. Pathomorphological examination of seven carcasses revealed acute and subacute malacia of the cerebellar grey matter. Additional acute malacic lesions located in the cerebral cortices and basal ganglia were observed. Mesencephalic nuclei were less severely affected and displayed acute changes. Despite intense search for environmental toxins and infectious agents, the cause of the fatalities remained undetermined. However, the type and pattern of the lesions are most suggestive of a thiamine deficiency.

  • References6
  • Citations3


  • References6
  • Citations3


Mentioned in this Paper

Thiamine Deficiency
Vitamin B Complex
Gray Matter
Multicystic Encephalomalacia
Disease Outbreaks
Entire Basal Nuclei

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