Poly-L-lactic acid: consultation on the injection techniques

Journal of the European Academy of Dermatology and Venereology : JEADV
Danny Vleggaar

Abstract

When poly-L-lactic acid (PLLA) was first introduced (marketed as New-Fill), incorrect injection technique was largely responsible for the manifestation of device-related adverse events in the form of subcutaneous papules and areas of induration. Now marketed as Sculptra, widespread clinical experience with injectable PLLA has resulted in a wealth of information on product reconstitution and correct injection technique. The injection techniques for the optimal use of injectable PLLA are detailed here. When injecting PLLA it is important to adhere to the product guidelines in terms of injection volume, depth and placement. As the material provides a gradual restoration of volume, PLLA should be injected conservatively, avoiding the possibility of overcorrection. Injections should be sufficiently deep to avoid areas of induration in the superficial layers of the dermis. Areas above hypermobile muscles should also be avoided to prevent localized coalescence of injected material. While utilization of a specific injection technique depends on the position and severity of the volume deficiency, all injections use a 26-gauge needle and are separated by 0.5-1.0 cm. In the lower face a 'criss-cross' and 'tunnelling' technique should be e...Continue Reading

References

May 1, 1971·Journal of Biomedical Materials Research·R K KulkarniF Leonard
Nov 1, 1966·Archives of Surgery·R K KulkarniF Leonard

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Citations

Jan 24, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Salim MohannaEduardo Gotuzzo
Mar 21, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Anetta E ReszkoJudy Farber
Mar 21, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Douglas R Mest, Gail M Humble
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Jun 6, 2020·Journal of Cosmetic Dermatology·Greg J GoodmanCatherine Porter
May 2, 2008·AIDS Care·A KavouniS E Barton

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