Poly(amido amine) and calcium phosphate nanocomposite remineralization of dentin in acidic solution without calcium phosphate ions

Dental Materials : Official Publication of the Academy of Dental Materials
Kunneng LiangHockin H K Xu

Abstract

Patients with dry mouth often have an acidic oral environment lacking saliva that provides calcium (Ca) and phosphate (P) ions. However, there has been no study on dentin remineralization by placing samples in an acidic solution without Ca and P ions. Previous studies used saliva-like solutions with neutral pH and Ca and P ions. Therefore, the objective of this study was to investigate a novel method of combining poly(amido amine) (PAMAM) with a composite of nanoparticles of amorphous calcium phosphate (NACP) on dentin remineralization in an acidic solution without Ca and P ions for the first time. Demineralized dentin specimens were tested into four groups: (1) dentin control, (2) dentin coated with PAMAM, (3) dentin with NACP nanocomposite, (4) dentin with PAMAM plus NACP composite. Specimens were treated with lactic acid at pH 4 without initial Ca and P ions for 21 days. Acid neutralization and Ca and P ion concentrations were measured. Dentin specimens were examined by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and hardness testing vs. remineralization efficacy. NACP composite had mechanical properties similar to commercial control composites (p>0.1). NACP composite neutralized acid and release...Continue Reading

Citations

May 10, 2019·International Journal of Oral Science·Kunneng LiangHockin H K Xu
Nov 8, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Renan Vinicius de AraújoJeanine Giarolla
Dec 29, 2020·Journal of Esthetic and Restorative Dentistry : Official Publication of the American Academy of Esthetic Dentistry ... [et Al.]·Natalia Almeida BastosGrace Mendonca De Souza
Aug 18, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Wen ZhouHockin H K Xu
Sep 29, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Klaus D Jandt, David C Watts
Aug 25, 2018·Dental Materials : Official Publication of the Academy of Dental Materials·Roberto Ruggiero Braga

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